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210 results

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Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers.
Zhang A, Lau NA, Wong A, Brown LG, Coleman IM, De Sarkar N, Li D, DeLucia DC, Labrecque MP, Nguyen HM, Conner JL, Dumpit RF, True LD, Lin DW, Corey E, Alumkal JJ, Nelson PS, Morrissey C, Lee JK. Zhang A, et al. Among authors: brown lg. Cancer Res Commun. 2023 Nov 20;3(11):2358-2374. doi: 10.1158/2767-9764.CRC-23-0250. Cancer Res Commun. 2023. PMID: 37823778 Free PMC article.
SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer.
Zhang X, Coleman IM, Brown LG, True LD, Kollath L, Lucas JM, Lam HM, Dumpit R, Corey E, Chéry L, Lakely B, Higano CS, Montgomery B, Roudier M, Lange PH, Nelson PS, Vessella RL, Morrissey C. Zhang X, et al. Among authors: brown lg. Clin Cancer Res. 2015 Oct 15;21(20):4698-708. doi: 10.1158/1078-0432.CCR-15-0157. Epub 2015 Jun 12. Clin Cancer Res. 2015. PMID: 26071481 Free PMC article.
Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer.
Corella AN, Cabiliza Ordonio MVA, Coleman I, Lucas JM, Kaipainen A, Nguyen HM, Sondheim D, Brown LG, True LD, Lee JK, MacPherson D, Nghiem P, Gulati R, Morrissey C, Corey E, Nelson PS. Corella AN, et al. Among authors: brown lg. Clin Cancer Res. 2020 Apr 1;26(7):1667-1677. doi: 10.1158/1078-0432.CCR-19-0775. Epub 2019 Dec 5. Clin Cancer Res. 2020. PMID: 31806643 Free PMC article.
RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.
Labrecque MP, Brown LG, Coleman IM, Lakely B, Brady NJ, Lee JK, Nguyen HM, Li D, Hanratty B, Haffner MC, Rickman DS, True LD, Lin DW, Lam HM, Alumkal JJ, Corey E, Nelson PS, Morrissey C. Labrecque MP, et al. Among authors: brown lg. Cancer Res. 2021 Sep 15;81(18):4736-4750. doi: 10.1158/0008-5472.CAN-21-0307. Epub 2021 Jul 26. Cancer Res. 2021. PMID: 34312180 Free PMC article.
Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases.
Haider M, Zhang X, Coleman I, Ericson N, True LD, Lam HM, Brown LG, Ketchanji M, Nghiem B, Lakely B, Coleman R, Montgomery B, Lange PH, Roudier M, Higano CS, Bielas JH, Nelson PS, Vessella RL, Morrissey C. Haider M, et al. Among authors: brown lg. Clin Exp Metastasis. 2016 Mar;33(3):239-48. doi: 10.1007/s10585-015-9773-7. Epub 2015 Dec 14. Clin Exp Metastasis. 2016. PMID: 26667932 Free PMC article.
Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer.
Kumar A, Coleman I, Morrissey C, Zhang X, True LD, Gulati R, Etzioni R, Bolouri H, Montgomery B, White T, Lucas JM, Brown LG, Dumpit RF, DeSarkar N, Higano C, Yu EY, Coleman R, Schultz N, Fang M, Lange PH, Shendure J, Vessella RL, Nelson PS. Kumar A, et al. Among authors: brown lg. Nat Med. 2016 Apr;22(4):369-78. doi: 10.1038/nm.4053. Epub 2016 Feb 29. Nat Med. 2016. PMID: 26928463 Free PMC article.
Characterization of an Abiraterone Ultraresponsive Phenotype in Castration-Resistant Prostate Cancer Patient-Derived Xenografts.
Lam HM, McMullin R, Nguyen HM, Coleman I, Gormley M, Gulati R, Brown LG, Holt SK, Li W, Ricci DS, Verstraeten K, Thomas S, Mostaghel EA, Nelson PS, Vessella RL, Corey E. Lam HM, et al. Among authors: brown lg. Clin Cancer Res. 2017 May 1;23(9):2301-2312. doi: 10.1158/1078-0432.CCR-16-2054. Epub 2016 Dec 19. Clin Cancer Res. 2017. PMID: 27993966 Free PMC article.
210 results