Leferink NGH - Search Results

1

Decoding Catalysis by Terpene Synthases.

Whitehead JN, Leferink NGH, Johannissen LO, Hay S, Scrutton NS. Whitehead JN, et al. Among authors: leferink ngh. ACS Catal. 2023 Sep 15;13(19):12774-12802. doi: 10.1021/acscatal.3c03047. eCollection 2023 Oct 6. ACS Catal. 2023. PMID: 37822860 Free PMC article. Review.

2

Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic Trap.

Hedison TM, Leferink NG, Hay S, Scrutton NS. Hedison TM, et al. ACS Catal. 2016 Aug 5;6(8):5170-5180. doi: 10.1021/acscatal.6b01280. Epub 2016 Jun 28. ACS Catal. 2016. PMID: 27563493 Free PMC article.

3

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.

Karuppiah V, Ranaghan KE, Leferink NGH, Johannissen LO, Shanmugam M, Ní Cheallaigh A, Bennett NJ, Kearsey LJ, Takano E, Gardiner JM, van der Kamp MW, Hay S, Mulholland AJ, Leys D, Scrutton NS. Karuppiah V, et al. Among authors: leferink ngh. ACS Catal. 2017 Sep 1;7(9):6268-6282. doi: 10.1021/acscatal.7b01924. Epub 2017 Aug 9. ACS Catal. 2017. PMID: 28966840 Free PMC article.

4

Predictive Engineering of Class I Terpene Synthases Using Experimental and Computational Approaches.

Leferink NGH, Scrutton NS. Leferink NGH, et al. Chembiochem. 2022 Mar 4;23(5):e202100484. doi: 10.1002/cbic.202100484. Epub 2021 Nov 3. Chembiochem. 2022. PMID: 34669250 Free PMC article. Review.

5

How a 10-epi-Cubebol Synthase Avoids Premature Reaction Quenching to Form a Tricyclic Product at High Purity.

Whitehead JN, Leferink NGH, Komati Reddy G, Levy CW, Hay S, Takano E, Scrutton NS. Whitehead JN, et al. Among authors: leferink ngh. ACS Catal. 2022 Oct 7;12(19):12123-12131. doi: 10.1021/acscatal.2c03155. Epub 2022 Sep 21. ACS Catal. 2022. PMID: 36249875 Free PMC article.

6

Energy landscapes and catalysis in nitric-oxide synthase.

Sobolewska-Stawiarz A, Leferink NGH, Fisher K, Heyes DJ, Hay S, Rigby SEJ, Scrutton NS. Sobolewska-Stawiarz A, et al. Among authors: leferink ngh. J Biol Chem. 2014 Apr 25;289(17):11725-11738. doi: 10.1074/jbc.M114.548834. Epub 2014 Mar 7. J Biol Chem. 2014. PMID: 24610812 Free PMC article.

7

Towards the free energy landscape for catalysis in mammalian nitric oxide synthases.

Leferink NG, Hay S, Rigby SE, Scrutton NS. Leferink NG, et al. FEBS J. 2015 Aug;282(16):3016-29. doi: 10.1111/febs.13171. Epub 2014 Dec 26. FEBS J. 2015. PMID: 25491181 Free article. Review.

8

Experiment and Simulation Reveal How Mutations in Functional Plasticity Regions Guide Plant Monoterpene Synthase Product Outcome.

Leferink NGH, Ranaghan KE, Karuppiah V, Currin A, van der Kamp MW, Mulholland AJ, Scrutton NS. Leferink NGH, et al. ACS Catal. 2019 May 15;8(5):3780-3791. doi: 10.1021/acscatal.8b00692. Epub 2018 Mar 24. ACS Catal. 2019. PMID: 31157124 Free PMC article.

9

Exploring novel bacterial terpene synthases.

Reddy GK, Leferink NGH, Umemura M, Ahmed ST, Breitling R, Scrutton NS, Takano E. Reddy GK, et al. Among authors: leferink ngh. PLoS One. 2020 Apr 30;15(4):e0232220. doi: 10.1371/journal.pone.0232220. eCollection 2020. PLoS One. 2020. PMID: 32353014 Free PMC article.

10

Molecular Determinants of Carbocation Cyclisation in Bacterial Monoterpene Synthases.

Leferink NGH, Escorcia AM, Ouwersloot BR, Johanissen LO, Hay S, van der Kamp MW, Scrutton NS. Leferink NGH, et al. Chembiochem. 2022 Mar 4;23(5):e202100688. doi: 10.1002/cbic.202100688. Epub 2022 Jan 19. Chembiochem. 2022. PMID: 35005823 Free PMC article.

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