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The alpha-adrenergic antagonist prazosin promotes cytosolic siRNA delivery from lysosomal compartments.
J Control Release. 2023 Dec;364:142-158. doi: 10.1016/j.jconrel.2023.10.014. Epub 2023 Oct 27.
J Control Release. 2023.
PMID: 37816483
Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells.
Joris F, De Backer L, Van de Vyver T, Bastiancich C, De Smedt SC, Raemdonck K.
Joris F, et al. Among authors: van de vyver t.
J Control Release. 2018 Jan 10;269:266-276. doi: 10.1016/j.jconrel.2017.11.019. Epub 2017 Nov 13.
J Control Release. 2018.
PMID: 29146245
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Cationic Amphiphilic Drugs Boost the Lysosomal Escape of Small Nucleic Acid Therapeutics in a Nanocarrier-Dependent Manner.
Van de Vyver T, Bogaert B, De Backer L, Joris F, Guagliardo R, Van Hoeck J, Merckx P, Van Calenbergh S, Ramishetti S, Peer D, Remaut K, De Smedt SC, Raemdonck K.
Van de Vyver T, et al.
ACS Nano. 2020 Apr 28;14(4):4774-4791. doi: 10.1021/acsnano.0c00666. Epub 2020 Apr 14.
ACS Nano. 2020.
PMID: 32250113
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Surfactant Protein B Promotes Cytosolic SiRNA Delivery by Adopting a Virus-like Mechanism of Action.
Guagliardo R, Herman L, Penders J, Zamborlin A, De Keersmaecker H, Van de Vyver T, Verstraeten S, Merckx P, Mingeot-Leclercq MP, Echaide M, Pérez-Gil J, Stevens MM, De Smedt SC, Raemdonck K.
Guagliardo R, et al. Among authors: van de vyver t.
ACS Nano. 2021 May 25;15(5):8095-8109. doi: 10.1021/acsnano.0c04489. Epub 2021 Mar 16.
ACS Nano. 2021.
PMID: 33724778
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Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics.
Van de Vyver T, De Smedt SC, Raemdonck K.
Van de Vyver T, et al.
Adv Drug Deliv Rev. 2022 Feb;181:114041. doi: 10.1016/j.addr.2021.114041. Epub 2021 Nov 8.
Adv Drug Deliv Rev. 2022.
PMID: 34763002
Review.
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Hydrogel-Induced Cell Membrane Disruptions Enable Direct Cytosolic Delivery of Membrane-Impermeable Cargo.
Van Hoeck J, Van de Vyver T, Harizaj A, Goetgeluk G, Merckx P, Liu J, Wels M, Sauvage F, De Keersmaecker H, Vanhove C, de Jong OG, Vader P, Dewitte H, Vandekerckhove B, Braeckmans K, De Smedt SC, Raemdonck K.
Van Hoeck J, et al. Among authors: van de vyver t.
Adv Mater. 2021 Jul;33(30):e2008054. doi: 10.1002/adma.202008054. Epub 2021 Jun 9.
Adv Mater. 2021.
PMID: 34106486
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Glycation in human fingernail clippings using ATR-FTIR spectrometry, a new marker for the diagnosis and monitoring of diabetes mellitus.
Coopman R, Van de Vyver T, Kishabongo AS, Katchunga P, Van Aken EH, Cikomola J, Monteyne T, Speeckaert MM, Delanghe JR.
Coopman R, et al. Among authors: van de vyver t.
Clin Biochem. 2017 Jan;50(1-2):62-67. doi: 10.1016/j.clinbiochem.2016.09.001. Epub 2016 Sep 4.
Clin Biochem. 2017.
PMID: 27598437
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