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Safety and efficacy of once-daily HU6 versus placebo in people with non-alcoholic fatty liver disease and high BMI: a randomised, double-blind, placebo-controlled, phase 2a trial.
Noureddin M, Khan S, Portell F, Jorkasky D, Dennis J, Khan O, Johansson L, Johansson E, Sanyal AJ. Noureddin M, et al. Among authors: portell f. Lancet Gastroenterol Hepatol. 2023 Dec;8(12):1094-1105. doi: 10.1016/S2468-1253(23)00198-X. Epub 2023 Oct 5. Lancet Gastroenterol Hepatol. 2023. PMID: 37806314 Clinical Trial.
Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.
Thomas RR, Khan SM, Portell FR, Smigrodzki RM, Bennett JP Jr. Thomas RR, et al. Among authors: portell fr. Mitochondrion. 2011 Jan;11(1):108-18. doi: 10.1016/j.mito.2010.08.004. Epub 2010 Aug 18. Mitochondrion. 2011. PMID: 20727424 Free PMC article.
RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency.
Ladd AC, Brohawn DG, Thomas RR, Keeney PM, Berr SS, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Bennett JP. Ladd AC, et al. Among authors: portell fr. Brain Res. 2017 Jul 15;1667:74-83. doi: 10.1016/j.brainres.2017.05.010. Epub 2017 May 13. Brain Res. 2017. PMID: 28511992
Maxillary first molar with six canals.
Bond JL, Hartwell G, Portell FR. Bond JL, et al. Among authors: portell fr. J Endod. 1988 May;14(5):258-60. doi: 10.1016/S0099-2399(88)80180-8. J Endod. 1988. PMID: 3251981 No abstract available.
13 results