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Synthesis by diastereomeric resolution, biochemical evaluation and molecular modelling of chiral 3-hydroxyl b-lactam microtubule-targeting agents for the treatment of triple negative breast and chemoresistant colorectal cancers.
Bioorg Chem. 2023 Dec;141:106877. doi: 10.1016/j.bioorg.2023.106877. Epub 2023 Sep 30.
Bioorg Chem. 2023.
PMID: 37804699
Free article.
Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review.
McLoughlin EC, O'Boyle NM.
McLoughlin EC, et al.
Pharmaceuticals (Basel). 2020 Jan 3;13(1):8. doi: 10.3390/ph13010008.
Pharmaceuticals (Basel). 2020.
PMID: 31947889
Free PMC article.
Review.
Item in Clipboard
Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β-Lactams.
McLoughlin EC, O'Brien JE, Trujillo C, Meegan MJ, O'Boyle NM.
McLoughlin EC, et al.
ChemistryOpen. 2023 Jun;12(6):e202200119. doi: 10.1002/open.202200119. Epub 2022 Jul 25.
ChemistryOpen. 2023.
PMID: 35876400
Free PMC article.
Item in Clipboard
Synthesis, Characterisation and Mechanism of Action of Anticancer 3-Fluoroazetidin-2-ones.
Malebari AM, Duffy Morales G, Twamley B, Fayne D, Khan MF, McLoughlin EC, O'Boyle NM, Zisterer DM, Meegan MJ.
Malebari AM, et al. Among authors: mcloughlin ec.
Pharmaceuticals (Basel). 2022 Aug 24;15(9):1044. doi: 10.3390/ph15091044.
Pharmaceuticals (Basel). 2022.
PMID: 36145265
Free PMC article.
Item in Clipboard
Correction: McLoughlin, E.C.; O'Boyle, N.M. Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review. Pharmaceuticals 2020, 13, 8.
McLoughlin EC, O'Boyle NM.
McLoughlin EC, et al.
Pharmaceuticals (Basel). 2020 Apr 20;13(4):72. doi: 10.3390/ph13040072.
Pharmaceuticals (Basel). 2020.
PMID: 32325955
Free PMC article.
Item in Clipboard
Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity.
Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, O'Boyle NM, McLoughlin E, Abdel-Samii ZK, Elshaier YAMM.
Ibrahim TS, et al.
Pharmaceuticals (Basel). 2020 Nov 15;13(11):393. doi: 10.3390/ph13110393.
Pharmaceuticals (Basel). 2020.
PMID: 33203182
Free PMC article.
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A scoping review of non-professional medication practices and medication safety outcomes during public health emergencies.
Kelly D, Koay A, Mineva G, Volz M, McCool A, McLoughlin E, Ó Conluain R, Sharma M, Kerr A, Franklin BD, Grimes T.
Kelly D, et al.
Public Health. 2023 Jan;214:50-60. doi: 10.1016/j.puhe.2022.10.026. Epub 2022 Dec 13.
Public Health. 2023.
PMID: 36521272
Review.
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