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Prediction of cancer treatment response from histopathology images through imputed transcriptomics.
Hoang DT, Dinstag G, Hermida LC, Ben-Zvi DS, Elis E, Caley K, Sammut SJ, Sinha S, Sinha N, Dampier CH, Stossel C, Patil T, Rajan A, Lassoued W, Strauss J, Bailey S, Allen C, Redman J, Beker T, Jiang P, Golan T, Wilkinson S, Sowalsky AG, Pine SR, Caldas C, Gulley JL, Aldape K, Aharonov R, Stone EA, Ruppin E. Hoang DT, et al. Among authors: caldas c. Res Sq [Preprint]. 2023 Sep 15:rs.3.rs-3193270. doi: 10.21203/rs.3.rs-3193270/v1. Res Sq. 2023. PMID: 37790315 Free PMC article. Preprint.
Prognostic Value of MammaPrint® in Invasive Lobular Breast Cancer.
Beumer IJ, Persoon M, Witteveen A, Dreezen C, Chin SF, Sammut SJ, Snel M, Caldas C, Linn S, van 't Veer LJ, Bernards R, Glas AM. Beumer IJ, et al. Among authors: caldas c. Biomark Insights. 2016 Dec 11;11:139-146. doi: 10.4137/BMI.S38435. eCollection 2016. Biomark Insights. 2016. PMID: 27980389 Free PMC article.
Next Generation-Targeted Amplicon Sequencing (NG-TAS): an optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA.
Gao M, Callari M, Beddowes E, Sammut SJ, Grzelak M, Biggs H, Jones L, Boumertit A, Linn SC, Cortes J, Oliveira M, Baird R, Chin SF, Caldas C. Gao M, et al. Among authors: caldas c. Genome Med. 2019 Jan 4;11(1):1. doi: 10.1186/s13073-018-0611-9. Genome Med. 2019. PMID: 30609936 Free PMC article. Clinical Trial.
Multi-omic machine learning predictor of breast cancer therapy response.
Sammut SJ, Crispin-Ortuzar M, Chin SF, Provenzano E, Bardwell HA, Ma W, Cope W, Dariush A, Dawson SJ, Abraham JE, Dunn J, Hiller L, Thomas J, Cameron DA, Bartlett JMS, Hayward L, Pharoah PD, Markowetz F, Rueda OM, Earl HM, Caldas C. Sammut SJ, et al. Among authors: caldas c. Nature. 2022 Jan;601(7894):623-629. doi: 10.1038/s41586-021-04278-5. Epub 2021 Dec 7. Nature. 2022. PMID: 34875674 Free PMC article.
Comparison of tumor-informed and tumor-naïve sequencing assays for ctDNA detection in breast cancer.
Santonja A, Cooper WN, Eldridge MD, Edwards PAW, Morris JA, Edwards AR, Zhao H, Heider K, Couturier DL, Vijayaraghavan A, Mennea P, Ditter EJ, Smith CG, Boursnell C, Manzano García R, Rueda OM, Beddowes E, Biggs H, Sammut SJ, Rosenfeld N, Caldas C, Abraham JE, Gale D. Santonja A, et al. Among authors: caldas c. EMBO Mol Med. 2023 Jun 7;15(6):e16505. doi: 10.15252/emmm.202216505. Epub 2023 May 10. EMBO Mol Med. 2023. PMID: 37161793 Free PMC article.
A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.
Bruna A, Rueda OM, Greenwood W, Batra AS, Callari M, Batra RN, Pogrebniak K, Sandoval J, Cassidy JW, Tufegdzic-Vidakovic A, Sammut SJ, Jones L, Provenzano E, Baird R, Eirew P, Hadfield J, Eldridge M, McLaren-Douglas A, Barthorpe A, Lightfoot H, O'Connor MJ, Gray J, Cortes J, Baselga J, Marangoni E, Welm AL, Aparicio S, Serra V, Garnett MJ, Caldas C. Bruna A, et al. Among authors: caldas c. Cell. 2016 Sep 22;167(1):260-274.e22. doi: 10.1016/j.cell.2016.08.041. Epub 2016 Sep 15. Cell. 2016. PMID: 27641504 Free PMC article.
Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers.
Chin SF, Santonja A, Grzelak M, Ahn S, Sammut SJ, Clifford H, Rueda OM, Pugh M, Goldgraben MA, Bardwell HA, Cho EY, Provenzano E, Rojo F, Alba E, Caldas C. Chin SF, et al. Among authors: caldas c. Exp Mol Pathol. 2018 Jun;104(3):161-169. doi: 10.1016/j.yexmp.2018.03.006. Epub 2018 Mar 31. Exp Mol Pathol. 2018. PMID: 29608913 Free PMC article.
Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.
Rueda OM, Sammut SJ, Seoane JA, Chin SF, Caswell-Jin JL, Callari M, Batra R, Pereira B, Bruna A, Ali HR, Provenzano E, Liu B, Parisien M, Gillett C, McKinney S, Green AR, Murphy L, Purushotham A, Ellis IO, Pharoah PD, Rueda C, Aparicio S, Caldas C, Curtis C. Rueda OM, et al. Among authors: caldas c. Nature. 2019 Mar;567(7748):399-404. doi: 10.1038/s41586-019-1007-8. Epub 2019 Mar 13. Nature. 2019. PMID: 30867590 Free PMC article.
690 results