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A disordered region controls cBAF activity via condensation and partner recruitment.
Patil A, Strom AR, Paulo JA, Collings CK, Ruff KM, Shinn MK, Sankar A, Cervantes KS, Wauer T, St Laurent JD, Xu G, Becker LA, Gygi SP, Pappu RV, Brangwynne CP, Kadoch C. Patil A, et al. Among authors: strom ar. Cell. 2023 Oct 26;186(22):4936-4955.e26. doi: 10.1016/j.cell.2023.08.032. Epub 2023 Oct 3. Cell. 2023. PMID: 37788668 Free article.
Viscoelasticity and advective flow of RNA underlies nucleolar form and function.
Riback JA, Eeftens JM, Lee DSW, Quinodoz SA, Donlic A, Orlovsky N, Wiesner L, Beckers L, Becker LA, Strom AR, Rana U, Tolbert M, Purse BW, Kleiner R, Kriwacki R, Brangwynne CP. Riback JA, et al. Among authors: strom ar. Mol Cell. 2023 Sep 7;83(17):3095-3107.e9. doi: 10.1016/j.molcel.2023.08.006. Mol Cell. 2023. PMID: 37683610 Free PMC article.
Interplay of condensation and chromatin binding underlies BRD4 targeting.
Strom AR, Eeftens JM, Polyachenko Y, Weaver CJ, Watanabe HF, Bracha D, Orlovsky ND, Jumper CC, Jacobs WM, Brangwynne CP. Strom AR, et al. Mol Biol Cell. 2024 Jun 1;35(6):ar88. doi: 10.1091/mbc.E24-01-0046. Epub 2024 Apr 24. Mol Biol Cell. 2024. PMID: 38656803
The mechanobiology of nuclear phase separation.
Lee DSW, Strom AR, Brangwynne CP. Lee DSW, et al. Among authors: strom ar. APL Bioeng. 2022 Apr 28;6(2):021503. doi: 10.1063/5.0083286. eCollection 2022 Jun. APL Bioeng. 2022. PMID: 35540725 Free PMC article. Review.
Compartmentalization of telomeres through DNA-scaffolded phase separation.
Jack A, Kim Y, Strom AR, Lee DSW, Williams B, Schaub JM, Kellogg EH, Finkelstein IJ, Ferro LS, Yildiz A, Brangwynne CP. Jack A, et al. Among authors: strom ar. Dev Cell. 2022 Jan 24;57(2):277-290.e9. doi: 10.1016/j.devcel.2021.12.017. Dev Cell. 2022. PMID: 35077681 Free PMC article.
Nucleated transcriptional condensates amplify gene expression.
Wei MT, Chang YC, Shimobayashi SF, Shin Y, Strom AR, Brangwynne CP. Wei MT, et al. Among authors: strom ar. Nat Cell Biol. 2020 Oct;22(10):1187-1196. doi: 10.1038/s41556-020-00578-6. Epub 2020 Sep 14. Nat Cell Biol. 2020. PMID: 32929202
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
Sanders DW, Kedersha N, Lee DSW, Strom AR, Drake V, Riback JA, Bracha D, Eeftens JM, Iwanicki A, Wang A, Wei MT, Whitney G, Lyons SM, Anderson P, Jacobs WM, Ivanov P, Brangwynne CP. Sanders DW, et al. Among authors: strom ar. Cell. 2020 Apr 16;181(2):306-324.e28. doi: 10.1016/j.cell.2020.03.050. Cell. 2020. PMID: 32302570 Free PMC article.
62 results