Pappu RV - Search Results

1

A disordered region controls cBAF activity via condensation and partner recruitment.

Patil A, Strom AR, Paulo JA, Collings CK, Ruff KM, Shinn MK, Sankar A, Cervantes KS, Wauer T, St Laurent JD, Xu G, Becker LA, Gygi SP, Pappu RV, Brangwynne CP, Kadoch C. Patil A, et al. Among authors: pappu rv. Cell. 2023 Oct 26;186(22):4936-4955.e26. doi: 10.1016/j.cell.2023.08.032. Epub 2023 Oct 3. Cell. 2023. PMID: 37788668 Free article.

2

Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins.

Halfmann R, Alberti S, Krishnan R, Lyle N, O'Donnell CW, King OD, Berger B, Pappu RV, Lindquist S. Halfmann R, et al. Among authors: pappu rv. Mol Cell. 2011 Jul 8;43(1):72-84. doi: 10.1016/j.molcel.2011.05.013. Mol Cell. 2011. PMID: 21726811 Free PMC article.

3

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation.

Crick SL, Ruff KM, Garai K, Frieden C, Pappu RV. Crick SL, et al. Among authors: pappu rv. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20075-80. doi: 10.1073/pnas.1320626110. Epub 2013 Nov 26. Proc Natl Acad Sci U S A. 2013. PMID: 24282292 Free PMC article.

4

A coarse-grained model for polyglutamine aggregation modulated by amphipathic flanking sequences.

Ruff KM, Khan SJ, Pappu RV. Ruff KM, et al. Among authors: pappu rv. Biophys J. 2014 Sep 2;107(5):1226-1235. doi: 10.1016/j.bpj.2014.07.019. Biophys J. 2014. PMID: 25185558 Free PMC article.

5

Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome.

Ripaud L, Chumakova V, Antonin M, Hastie AR, Pinkert S, Körner R, Ruff KM, Pappu RV, Hornburg D, Mann M, Hartl FU, Hipp MS. Ripaud L, et al. Among authors: pappu rv. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18219-24. doi: 10.1073/pnas.1421313111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489109 Free PMC article.

6

Relating sequence encoded information to form and function of intrinsically disordered proteins.

Das RK, Ruff KM, Pappu RV. Das RK, et al. Among authors: pappu rv. Curr Opin Struct Biol. 2015 Jun;32:102-12. doi: 10.1016/j.sbi.2015.03.008. Epub 2015 Apr 2. Curr Opin Struct Biol. 2015. PMID: 25863585 Free PMC article. Review.

7

CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences.

Ruff KM, Harmon TS, Pappu RV. Ruff KM, et al. Among authors: pappu rv. J Chem Phys. 2015 Dec 28;143(24):243123. doi: 10.1063/1.4935066. J Chem Phys. 2015. PMID: 26723608 Free PMC article.

8

Coexisting Liquid Phases Underlie Nucleolar Subcompartments.

Feric M, Vaidya N, Harmon TS, Mitrea DM, Zhu L, Richardson TM, Kriwacki RW, Pappu RV, Brangwynne CP. Feric M, et al. Among authors: pappu rv. Cell. 2016 Jun 16;165(7):1686-1697. doi: 10.1016/j.cell.2016.04.047. Epub 2016 May 19. Cell. 2016. PMID: 27212236 Free PMC article.

9

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein.

Pak CW, Kosno M, Holehouse AS, Padrick SB, Mittal A, Ali R, Yunus AA, Liu DR, Pappu RV, Rosen MK. Pak CW, et al. Among authors: pappu rv. Mol Cell. 2016 Jul 7;63(1):72-85. doi: 10.1016/j.molcel.2016.05.042. Mol Cell. 2016. PMID: 27392146 Free PMC article.

10

Monomeric Huntingtin Exon 1 Has Similar Overall Structural Features for Wild-Type and Pathological Polyglutamine Lengths.

Warner JB 4th, Ruff KM, Tan PS, Lemke EA, Pappu RV, Lashuel HA. Warner JB 4th, et al. Among authors: pappu rv. J Am Chem Soc. 2017 Oct 18;139(41):14456-14469. doi: 10.1021/jacs.7b06659. Epub 2017 Oct 9. J Am Chem Soc. 2017. PMID: 28937758 Free PMC article.

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