Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

13,163 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer's disease pathology progression.
Ando K, Küçükali F, Doeraene E, Nagaraj S, Antonelli EM, Thazin Htut M, Yilmaz Z, Kosa AC, Lopez-Guitierrez L, Quintanilla-Sánchez C, Aydin E, Ramos AR, Mansour S, Turbant S, Schurmans S, Sleegers K, Erneux C, Brion JP, Leroy K; Brain Bank NeuroCEB Neuropathology Network. Ando K, et al. Acta Neuropathol. 2024 Jun 4;147(1):94. doi: 10.1007/s00401-024-02745-7. Acta Neuropathol. 2024. PMID: 38833073
While INPPL1 has been identified as one of the most significant genes whose RNA expression correlates with cognitive decline, the potential alteration of SHIP2 expression and localization during the progression of AD remains largely unknown. ...
While INPPL1 has been identified as one of the most significant genes whose RNA expression correlates with cognitive decline, the pot …
Whole genome sequencing of HER2-positive metastatic extramammary Paget's disease: a case report.
Lim BY, Guo Z, Lim JQ, Ko TK, Lee ECY, Kannan B, Lee JY, Lim AH, Li Z, Ng CC, Busmanis I, Chan JY. Lim BY, et al. Orphanet J Rare Dis. 2024 Jun 3;19(1):223. doi: 10.1186/s13023-024-03169-y. Orphanet J Rare Dis. 2024. PMID: 38831459 Free PMC article.
RESULTS: Notable copy number gains (log(2)FC > 0.9) on chromosomes 7 and 8 were detected (n = 81), with 92.6% of these unique genes specifically located on chromosome 8. Prominent cancer-associated genes include ZNF703, HOOK3, DDHD2, LSM1, NSD3, ADAM9, BRF2, KAT6 …
RESULTS: Notable copy number gains (log(2)FC > 0.9) on chromosomes 7 and 8 were detected (n = 81), with 92.6% of these unique genes …
Skin treatment with non-thermal plasma modulates the immune system through miR-223-3p and its target genes.
Engel A, Ludwig N, Grandke F, Wagner V, Kern F, Fehlmann T, Schmartz GP, Aparicio-Puerta E, Henn D, Walch-Rückheim B, Hannig M, Rupf S, Meese E, Laschke MW, Keller A. Engel A, et al. RNA Biol. 2024 Jan;21(1):31-44. doi: 10.1080/15476286.2024.2361571. Epub 2024 Jun 3. RNA Biol. 2024. PMID: 38828710
Notably, this miRNA, along with mmu-miR-142a-5p and mmu-miR-144-3p, regulates genes and pathways associated with wound healing and tissue regeneration (namely ErbB, FoxO, Hippo, and PI3K-Akt signalling). ...Finally, single-cell sequencing of PBMCs reveals the downre …
Notably, this miRNA, along with mmu-miR-142a-5p and mmu-miR-144-3p, regulates genes and pathways associated with wound healing and ti …
Molecular analysis of genetic mutations in non-small cell lung cancer in Morocco.
Morjani O, Benkirane N, Errihani H, Elfahime EM, Lakhiari H. Morjani O, et al. Pan Afr Med J. 2024 Mar 11;47:116. doi: 10.11604/pamj.2024.47.116.42973. eCollection 2024. Pan Afr Med J. 2024. PMID: 38828424 Free PMC article.
Anaplastic lymphoma kinase (ALK) gene fusion was observed in 3.19% of patients, and KRAS mutations in 1.06%. No mutations were found in other tested genes. A slightly higher mutation rate was noted in females (54.16%) compared to males (45.84%). ...
Anaplastic lymphoma kinase (ALK) gene fusion was observed in 3.19% of patients, and KRAS mutations in 1.06%. No mutations were found in othe …
[Correlation between common driver gene variations and clinicopathological typing in lung adenocarcinoma].
Ma XL, Jia RN, Han K, Zhang YX. Ma XL, et al. Zhonghua Bing Li Xue Za Zhi. 2024 Jun 8;53(6):578-584. doi: 10.3760/cma.j.cn112151-20231019-00277. Zhonghua Bing Li Xue Za Zhi. 2024. PMID: 38825903 Chinese.
Next-generation sequencing was used to detect variations in EGFR, KRAS, ALK, RET, ROS1, MET, HER2, or BRAF driver genes. Results: There were 2 384 males and 2 611 females. EGFR and ALK variations were more commonly found in female patients aged 60 years or older, with EGFR …
Next-generation sequencing was used to detect variations in EGFR, KRAS, ALK, RET, ROS1, MET, HER2, or BRAF driver genes. Results: The …
Gene alterations in the nuclear transport receptor superfamily: A study of head and neck cancer.
Nguyen PT, Shimojukkoku Y, Kajiya Y, Oku Y, Tomishima A, Shima K, Sasahira T. Nguyen PT, et al. PLoS One. 2024 May 31;19(5):e0300446. doi: 10.1371/journal.pone.0300446. eCollection 2024. PLoS One. 2024. PMID: 38820302 Free PMC article.
Furthermore, our study revealed that seven out of eight cell cycle genes (CDK1, CDK2, CDK4, CDK6, CCNA1, CCNB1, and CCNE2) were significantly and positively correlated with nuclear transport receptor genes in TCGA pancancer and CCLE datasets. Additionally, functiona …
Furthermore, our study revealed that seven out of eight cell cycle genes (CDK1, CDK2, CDK4, CDK6, CCNA1, CCNB1, and CCNE2) were signi …
Comparison of diagnostic performance between Oncomine Dx target test and AmoyDx panel for detecting actionable mutations in lung cancer.
Nagakubo Y, Hirotsu Y, Yoshino M, Amemiya K, Saito R, Kakizaki Y, Tsutsui T, Miyashita Y, Goto T, Omata M. Nagakubo Y, et al. Sci Rep. 2024 May 30;14(1):12480. doi: 10.1038/s41598-024-62857-8. Sci Rep. 2024. PMID: 38816489 Free PMC article.
Companion diagnostic (CDx) tests play important roles in identifying oncogenic driver genes and tailoring effective molecularly targeted therapies for lung cancer patients. ...Here, we performed a direct comparison analysis of 1059 genetic alterations of eight driver ge …
Companion diagnostic (CDx) tests play important roles in identifying oncogenic driver genes and tailoring effective molecularly targe …
Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity.
Houlahan KE, Khan A, Greenwald NF, Vivas CS, West RB, Angelo M, Curtis C. Houlahan KE, et al. Science. 2024 May 31;384(6699):eadh8697. doi: 10.1126/science.adh8697. Epub 2024 May 31. Science. 2024. PMID: 38815010
Interrogating 5870 breast cancer lesions, we demonstrated that germline-derived epitopes in recurrently amplified genes influence somatic evolution by mediating immunoediting. Individuals with a high germline-epitope burden in human epidermal growth factor receptor 2 (HER2 …
Interrogating 5870 breast cancer lesions, we demonstrated that germline-derived epitopes in recurrently amplified genes influence som …
The upregulation and transcriptional regulatory mechanisms of Extra spindle pole bodies like 1 in bladder cancer: An immunohistochemistry and high-throughput screening Evaluation.
Zhang W, Liang ZQ, He RQ, Huang ZG, Wang XM, Wei MY, Su HL, Liu ZS, Zheng YS, Huang WY, Zhang HJ, Dang YW, Li SH, Cheng JW, Chen G, He J. Zhang W, et al. Heliyon. 2024 May 15;10(10):e31192. doi: 10.1016/j.heliyon.2024.e31192. eCollection 2024 May 30. Heliyon. 2024. PMID: 38813236 Free PMC article.
ESPL1 was predominantly distributed in BC epithelial cells. Coexpressed genes of ESPL1 were enriched in cell cycle-related signalling pathways, and ESPL1 might be involved in the communication between epithelial and residual cells in the Hippo, ErbB, PI3K-Akt and Ra …
ESPL1 was predominantly distributed in BC epithelial cells. Coexpressed genes of ESPL1 were enriched in cell cycle-related signalling …
Characterization of Potential Target Genes of Borneol in Increasing Trastuzumab Sensitivity in HER2+ Trastuzumab-Resistant Breast Cancer: Bioinformatics and In Vitro Studies.
Lestari IA, Putra IMR, Fatimah N, Ujiantari NSO, Putri DDP, Hermawan A. Lestari IA, et al. Asian Pac J Cancer Prev. 2024 May 1;25(5):1623-1634. doi: 10.31557/APJCP.2024.25.5.1623. Asian Pac J Cancer Prev. 2024. PMID: 38809634 Free article.
However, its anticancer effect on HER2+ BC remains unknown. This study aimed to determine the potential target genes of BOR and its effect on overcoming the resistance of HER2+ BC to TRZ. ...CONCLUSION: BOR improved the cytotoxic effects of TRZ on HCC1954 and HCC1954-TR ce …
However, its anticancer effect on HER2+ BC remains unknown. This study aimed to determine the potential target genes of BOR and its e …
13,163 results
You have reached the last available page of results. Please see the User Guide for more information.