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Antidepressants enter cells, organelles, and membranes.
Blumenfeld Z, Bera K, Castrén E, Lester HA. Blumenfeld Z, et al. Among authors: castren e. Neuropsychopharmacology. 2024 Jan;49(1):246-261. doi: 10.1038/s41386-023-01725-x. Epub 2023 Oct 2. Neuropsychopharmacology. 2024. PMID: 37783840 Review.
Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brain.
Rantamäki T, Hendolin P, Kankaanpää A, Mijatovic J, Piepponen P, Domenici E, Chao MV, Männistö PT, Castrén E. Rantamäki T, et al. Among authors: castren e. Neuropsychopharmacology. 2007 Oct;32(10):2152-62. doi: 10.1038/sj.npp.1301345. Epub 2007 Feb 21. Neuropsychopharmacology. 2007. PMID: 17314919
Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants.
Jetsonen E, Didio G, Winkel F, Llach Pou M, Boj C, Kuczynski-Noyau L, Võikar V, Guirado R, Taira T, Lauri SE, Castrén E, Umemori J. Jetsonen E, et al. Among authors: castren e. Neuropsychopharmacology. 2023 Jun;48(7):1021-1030. doi: 10.1038/s41386-023-01562-y. Epub 2023 Mar 21. Neuropsychopharmacology. 2023. PMID: 36944718 Free PMC article.
Social Learning Requires Plasticity Enhanced by Fluoxetine Through Prefrontal Bdnf-TrkB Signaling to Limit Aggression Induced by Post-Weaning Social Isolation.
Mikics É, Guirado R, Umemori J, Tóth M, Biró L, Miskolczi C, Balázsfi D, Zelena D, Castrén E, Haller J, Karpova NN. Mikics É, et al. Among authors: castren e. Neuropsychopharmacology. 2018 Jan;43(2):235-245. doi: 10.1038/npp.2017.142. Epub 2017 Jul 7. Neuropsychopharmacology. 2018. PMID: 28685757 Free PMC article.
247 results