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Page 1
Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. Bacchus-Souffan C, et al. PLoS Pathog. 2021 Jan 19;17(1):e1009214. doi: 10.1371/journal.ppat.1009214. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33465157 Free PMC article.
HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives.
Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S. Morcilla V, et al. Among authors: bacchus souffan c. mBio. 2021 Oct 26;12(5):e0244721. doi: 10.1128/mBio.02447-21. Epub 2021 Sep 21. mBio. 2021. PMID: 34544282 Free PMC article.
The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells.
Duette G, Hiener B, Morgan H, Mazur FG, Mathivanan V, Horsburgh BA, Fisher K, Tong O, Lee E, Ahn H, Shaik A, Fromentin R, Hoh R, Bacchus-Souffan C, Nasr N, Cunningham AL, Hunt PW, Chomont N, Turville SG, Deeks SG, Kelleher AD, Schlub TE, Palmer S. Duette G, et al. Among authors: bacchus souffan c. J Clin Invest. 2022 Apr 1;132(7):e154422. doi: 10.1172/JCI154422. J Clin Invest. 2022. PMID: 35133986 Free PMC article.
Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission.
Chéret A, Bacchus-Souffan C, Avettand-Fenoël V, Mélard A, Nembot G, Blanc C, Samri A, Sáez-Cirión A, Hocqueloux L, Lascoux-Combe C, Allavena C, Goujard C, Valantin MA, Leplatois A, Meyer L, Rouzioux C, Autran B; OPTIPRIM ANRS-147 Study Group. Chéret A, et al. Among authors: bacchus souffan c. J Antimicrob Chemother. 2015 Jul;70(7):2108-20. doi: 10.1093/jac/dkv084. Epub 2015 Apr 21. J Antimicrob Chemother. 2015. PMID: 25900157 Clinical Trial.
Polyfunctional HIV-specific T cells in Post-Treatment Controllers.
Samri A, Bacchus-Souffan C, Hocqueloux L, Avettand-Fenoel V, Descours B, Theodorou I, Larsen M, Saez-Cirion A, Rouzioux C, Autran B; ANRS VISCONTI study group. Samri A, et al. Among authors: bacchus souffan c. AIDS. 2016 Sep 24;30(15):2299-302. doi: 10.1097/QAD.0000000000001195. AIDS. 2016. PMID: 27428742