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Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth.
Nakahara R, Aki S, Sugaya M, Hirose H, Kato M, Maeda K, Sakamoto DM, Kojima Y, Nishida M, Ando R, Muramatsu M, Pan M, Tsuchida R, Matsumura Y, Yanai H, Takano H, Yao R, Sando S, Shibuya M, Sakai J, Kodama T, Kidoya H, Shimamura T, Osawa T. Nakahara R, et al. Among authors: takano h. EMBO J. 2023 Nov 15;42(22):e114032. doi: 10.15252/embj.2023114032. Epub 2023 Oct 2. EMBO J. 2023. PMID: 37781951 Free PMC article.
IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer.
Sakahara M, Okamoto T, Oyanagi J, Takano H, Natsume Y, Yamanaka H, Kusama D, Fusejima M, Tanaka N, Mori S, Kawachi H, Ueno M, Sakai Y, Noda T, Nagayama S, Yao R. Sakahara M, et al. Among authors: takano h. Cancer Sci. 2019 Apr;110(4):1293-1305. doi: 10.1111/cas.13964. Epub 2019 Mar 22. Cancer Sci. 2019. PMID: 30724425 Free PMC article.
Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient.
Osumi H, Muroi A, Sakahara M, Kawachi H, Okamoto T, Natsume Y, Yamanaka H, Takano H, Kusama D, Shinozaki E, Ooki A, Yamaguchi K, Ueno M, Takeuchi K, Noda T, Nagayama S, Koshikawa N, Yao R. Osumi H, et al. Among authors: takano h. Sci Rep. 2020 Oct 15;10(1):17455. doi: 10.1038/s41598-020-74530-x. Sci Rep. 2020. PMID: 33060766 Free PMC article.
Inhibition of Crmp1 Phosphorylation at Ser522 Ameliorates Motor Function and Neuronal Pathology in Amyotrophic Lateral Sclerosis Model Mice.
Asano T, Nakamura H, Kawamoto Y, Tada M, Kimura Y, Takano H, Yao R, Saito H, Ikeda T, Komiya H, Kubota S, Hashiguchi S, Takahashi K, Kunii M, Tanaka K, Goshima Y, Nakamura F, Takeuchi H, Doi H, Tanaka F. Asano T, et al. Among authors: takano h. eNeuro. 2022 May 23;9(3):ENEURO.0133-22.2022. doi: 10.1523/ENEURO.0133-22.2022. Print 2022 May-Jun. eNeuro. 2022. PMID: 35523582 Free PMC article.
TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling.
Kawasaki N, Isogaya K, Dan S, Yamori T, Takano H, Yao R, Morishita Y, Taguchi L, Morikawa M, Heldin CH, Noda T, Ehata S, Miyazono K, Koinuma D. Kawasaki N, et al. Among authors: takano h. Cell Discov. 2018 Jan 9;4:1. doi: 10.1038/s41421-017-0001-2. eCollection 2018. Cell Discov. 2018. PMID: 29423269 Free PMC article.
Alpha-catenin is essential in intestinal adenoma formation.
Shibata H, Takano H, Ito M, Shioya H, Hirota M, Matsumoto H, Kakudo Y, Ishioka C, Akiyama T, Kanegae Y, Saito I, Noda T. Shibata H, et al. Among authors: takano h. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18199-204. doi: 10.1073/pnas.0705730104. Epub 2007 Nov 7. Proc Natl Acad Sci U S A. 2007. PMID: 17989230 Free PMC article.
The RNA-binding protein HuD regulates neuronal cell identity and maturation.
Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara S, Takano H, Takano T, Takahashi T, Noda T, Okano H. Akamatsu W, et al. Among authors: takano h, takano t. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4625-30. doi: 10.1073/pnas.0407523102. Epub 2005 Mar 11. Proc Natl Acad Sci U S A. 2005. PMID: 15764704 Free PMC article.
1,968 results