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ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination.
Jones JK, Zhang H, Lyne AM, Cavalli FMG, Hassen WE, Stevenson K, Kornahrens R, Yang Y, Li S, Dell S, Reitman ZJ, Herndon JE 2nd, Hoj J, Pendergast AM, Thompson EM. Jones JK, et al. Among authors: lyne am. Neurooncol Adv. 2023 Aug 7;5(1):vdad095. doi: 10.1093/noajnl/vdad095. eCollection 2023 Jan-Dec. Neurooncol Adv. 2023. PMID: 37781087 Free PMC article.
CD155 is a putative therapeutic target in medulloblastoma.
Li S, McLendon R, Sankey E, Kornahrens R, Lyne AM, Cavalli FMG, McKay Z, Herndon JE 2nd, Remke M, Picard D, Gromeier M, Brown M, Thompson EM. Li S, et al. Among authors: lyne am. Clin Transl Oncol. 2023 Mar;25(3):696-705. doi: 10.1007/s12094-022-02975-9. Epub 2022 Oct 27. Clin Transl Oncol. 2023. PMID: 36301489
VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance.
Pichol-Thievend C, Anezo O, Pettiwala AM, Bourmeau G, Montagne R, Lyne AM, Guichet PO, Deshors P, Ballestín A, Blanchard B, Reveilles J, Ravi VM, Joseph K, Heiland DH, Julien B, Leboucher S, Besse L, Legoix P, Dingli F, Liva S, Loew D, Giani E, Ribecco V, Furumaya C, Marcos-Kovandzic L, Masliantsev K, Daubon T, Wang L, Diaz AA, Schnell O, Beck J, Servant N, Karayan-Tapon L, Cavalli FMG, Seano G. Pichol-Thievend C, et al. Among authors: lyne am. Nat Commun. 2024 Apr 29;15(1):3602. doi: 10.1038/s41467-024-47985-z. Nat Commun. 2024. PMID: 38684700 Free PMC article.
Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma.
André-Grégoire G, Maghe C, Douanne T, Rosińska S, Spinelli F, Thys A, Trillet K, Jacobs KA, Ballu C, Dupont A, Lyne AM, Cavalli FMG, Busnelli I, Hyenne V, Goetz JG, Bidère N, Gavard J. André-Grégoire G, et al. Among authors: lyne am. iScience. 2022 Sep 13;25(10):105118. doi: 10.1016/j.isci.2022.105118. eCollection 2022 Oct 21. iScience. 2022. PMID: 36185361 Free PMC article.
H3K27me3 conditions chemotolerance in triple-negative breast cancer.
Marsolier J, Prompsy P, Durand A, Lyne AM, Landragin C, Trouchet A, Bento ST, Eisele A, Foulon S, Baudre L, Grosselin K, Bohec M, Baulande S, Dahmani A, Sourd L, Letouzé E, Salomon AV, Marangoni E, Perié L, Vallot C. Marsolier J, et al. Among authors: lyne am. Nat Genet. 2022 Apr;54(4):459-468. doi: 10.1038/s41588-022-01047-6. Epub 2022 Apr 11. Nat Genet. 2022. PMID: 35410383 Free PMC article.
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