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AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.
Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, Platt RJ, Chen S. Chow RD, et al. Among authors: platt rj. Nat Neurosci. 2017 Oct;20(10):1329-1341. doi: 10.1038/nn.4620. Epub 2017 Aug 14. Nat Neurosci. 2017. PMID: 28805815 Free PMC article.
Transcriptional linkage analysis with in vivo AAV-Perturb-seq.
Santinha AJ, Klingler E, Kuhn M, Farouni R, Lagler S, Kalamakis G, Lischetti U, Jabaudon D, Platt RJ. Santinha AJ, et al. Among authors: platt rj. Nature. 2023 Oct;622(7982):367-375. doi: 10.1038/s41586-023-06570-y. Epub 2023 Sep 20. Nature. 2023. PMID: 37730998 Free PMC article.
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.
Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Joung J, et al. Among authors: platt rj. Nat Protoc. 2017 Apr;12(4):828-863. doi: 10.1038/nprot.2017.016. Epub 2017 Mar 23. Nat Protoc. 2017. PMID: 28333914 Free PMC article.
Multiplexed Genome Engineering with Cas12a.
Weisbach NR, Meijs A, Platt RJ. Weisbach NR, et al. Among authors: platt rj. Methods Mol Biol. 2021;2312:171-192. doi: 10.1007/978-1-0716-1441-9_11. Methods Mol Biol. 2021. PMID: 34228291
Temporal controls over inter-areal cortical projection neuron fate diversity.
Klingler E, Tomasello U, Prados J, Kebschull JM, Contestabile A, Galiñanes GL, Fièvre S, Santinha A, Platt R, Huber D, Dayer A, Bellone C, Jabaudon D. Klingler E, et al. Nature. 2021 Nov;599(7885):453-457. doi: 10.1038/s41586-021-04048-3. Epub 2021 Nov 9. Nature. 2021. PMID: 34754107
36 results