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TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D. Drané P, et al. Among authors: detappe a. Nature. 2017 Mar 9;543(7644):211-216. doi: 10.1038/nature21358. Epub 2017 Feb 27. Nature. 2017. PMID: 28241136 Free PMC article.
Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein.
Botuyan MV, Cui G, Drané P, Oliveira C, Detappe A, Brault ME, Parnandi N, Chaubey S, Thompson JR, Bragantini B, Zhao D, Chapman JR, Chowdhury D, Mer G. Botuyan MV, et al. Among authors: detappe a. Nat Struct Mol Biol. 2018 Jul;25(7):591-600. doi: 10.1038/s41594-018-0083-z. Epub 2018 Jul 2. Nat Struct Mol Biol. 2018. PMID: 29967538 Free PMC article.
DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
He YJ, Meghani K, Caron MC, Yang C, Ronato DA, Bian J, Sharma A, Moore J, Niraj J, Detappe A, Doench JG, Legube G, Root DE, D'Andrea AD, Drané P, De S, Konstantinopoulos PA, Masson JY, Chowdhury D. He YJ, et al. Among authors: detappe a. Nature. 2018 Nov;563(7732):522-526. doi: 10.1038/s41586-018-0670-5. Epub 2018 Oct 31. Nature. 2018. PMID: 30464262 Free PMC article.
Corrigendum to "Advanced multimodal nanoparticles delay tumor progression withclinical radiation therapy" [Journal of Controlled Release 238 (2016) 103-133].
Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R. Detappe A, et al. J Control Release. 2021 Jan 10;329:1283-1285. doi: 10.1016/j.jconrel.2020.08.029. Epub 2020 Sep 23. J Control Release. 2021. PMID: 32977991 No abstract available.
Publisher Correction: Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer.
Qi R, Wang Y, Bruno PM, Xiao H, Yu Y, Li T, Lauffer S, Wei W, Chen Q, Kang X, Song H, Yang X, Huang X, Detappe A, Matulonis U, Pepin D, Hemann MT, Birrer MJ, Ghoroghchian PP. Qi R, et al. Among authors: detappe a. Nat Commun. 2018 Feb 7;9(1):628. doi: 10.1038/s41467-018-02963-0. Nat Commun. 2018. PMID: 29416025 Free PMC article.
62 results