Tirona RG - Search Results

1

Differential effects of OATP2B1 on statin accumulation and toxicity in a beta cell model.

Kwon J, Kim MS, Blagojevic C, Mailloux J, Medwid S, Tirona RG, Wang R, Schwarz UI. Kwon J, et al. Among authors: tirona rg. Toxicol Mech Methods. 2024 Feb;34(2):130-147. doi: 10.1080/15376516.2023.2262568. Epub 2024 Jan 29. Toxicol Mech Methods. 2024. PMID: 37771097

2

Aging and brain free cholesterol concentration on amyloid-β peptide accumulation in guinea pigs.

Pang KS, Peng HB, Li BP, Wen B, Noh K, Xia R, Toscan A, Serson S, Fraser PE, Tirona RG, de Lannoy IAM. Pang KS, et al. Among authors: tirona rg. Biopharm Drug Dispos. 2024 Apr;45(2):93-106. doi: 10.1002/bdd.2386. Epub 2024 Mar 15. Biopharm Drug Dispos. 2024. PMID: 38488691

3

Prediction of the Renal Organic Anion Transporter 1 (OAT1)- Mediated Drug Interactions for LY404039, the Active Metabolite of Pomaglumetad Methionil.

Pak YA, Posada MM, Bacon J, Long A, Annes W, Witcher J, Mitchell M, Tirona RG, Hall SD, Hillgren KM. Pak YA, et al. Among authors: tirona rg. Pharm Res. 2023 Nov;40(11):2499-2511. doi: 10.1007/s11095-022-03464-y. Epub 2023 Jan 12. Pharm Res. 2023. PMID: 36635486

4

Investigation of N,N,N-Trimethyl-L-alanyl-L-proline Betaine (TMAP) as a Biomarker of Kidney Function.

Sidor NA, Velenosi TJ, Lajoie GA, Filler G, House AA, Weir MA, Thomson BK, Garg AX, Renaud JB, McDowell T, Knauer MJ, Tirona RG, Noble R, Selby N, Taal M, Urquhart BL. Sidor NA, et al. Among authors: tirona rg. ACS Omega. 2023 Apr 21;8(17):15160-15167. doi: 10.1021/acsomega.3c00153. eCollection 2023 May 2. ACS Omega. 2023. PMID: 37151562 Free PMC article.

5

Medication Prescribed Within One Year Preceding Fall-Related Injuries in Ontario Older Adults.

Ming Y, Zecevic AA, Booth RG, Hunter SW, Tirona RG, Johnson AM. Ming Y, et al. Among authors: tirona rg. Can Geriatr J. 2022 Dec 1;25(4):347-367. doi: 10.5770/cgj.25.569. eCollection 2022 Dec. Can Geriatr J. 2022. PMID: 36505916 Free PMC article.

6

Thiopurine Methyltransferase Intermediate Metabolizer Status and Thiopurine-Associated Toxicity During Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia.

Schwarz UI, Woldanski-Travaglini M, Swanston V, Mikhail M, Cacciotti C, Cairney E, Patel S, Seelisch J, Tole S, Wilejto M, Tirona RG, Kim RB, Zorzi AP. Schwarz UI, et al. Among authors: tirona rg. Clin Pharmacol Ther. 2023 Jun;113(6):1326-1336. doi: 10.1002/cpt.2894. Epub 2023 Apr 3. Clin Pharmacol Ther. 2023. PMID: 36932910

7

Significance of the Vitamin D Receptor on Crosstalk with Nuclear Receptors and Regulation of Enzymes and Transporters.

Noh K, Chow ECY, Quach HP, Groothuis GMM, Tirona RG, Pang KS. Noh K, et al. Among authors: tirona rg. AAPS J. 2022 Jun 1;24(4):71. doi: 10.1208/s12248-022-00719-9. AAPS J. 2022. PMID: 35650371 Review.

8

Association of Sex With Stroke and Bleeding Risk of Apixaban and Rivaroxaban in Elderly Atrial Fibrillation Patients Using Propensity Score Weights.

Gulilat M, Jandoc R, Jeyakumar N, McArthur E, Garg AX, Kim RB, Tirona RG, Schwarz UI. Gulilat M, et al. Among authors: tirona rg. CJC Open. 2021 Sep 10;4(1):56-64. doi: 10.1016/j.cjco.2021.09.002. eCollection 2022 Jan. CJC Open. 2021. PMID: 35072028 Free PMC article.

9

In-vitro characterization of coding variants with predicted functional implications in the efflux transporter multidrug resistance protein 4 (MRP4, ABCC4).

Mailloux J, Medwid S, Facey A, Sung I, Russell LE, Tirona RG, Kim RB, Schwarz UI. Mailloux J, et al. Among authors: tirona rg. Pharmacogenet Genomics. 2022 Apr 1;32(3):111-116. doi: 10.1097/FPC.0000000000000459. Pharmacogenet Genomics. 2022. PMID: 34693929

10

Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates.

Medwid S, Price HR, Taylor DP, Mailloux J, Schwarz UI, Kim RB, Tirona RG. Medwid S, et al. Among authors: tirona rg. Front Pharmacol. 2021 Sep 14;12:713567. doi: 10.3389/fphar.2021.713567. eCollection 2021. Front Pharmacol. 2021. PMID: 34594217 Free PMC article.

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