Hotta A - Search Results

1

iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome.

Hirayama R, Toyohara K, Watanabe K, Otsuki T, Araoka T, Mae SI, Horinouchi T, Yamamura T, Okita K, Hotta A, Iijima K, Nozu K, Osafune K. Hirayama R, et al. Among authors: hotta a. Commun Biol. 2023 Sep 28;6(1):854. doi: 10.1038/s42003-023-05203-4. Commun Biol. 2023. PMID: 37770589 Free PMC article.

2

Direct comparison of autologous and allogeneic transplantation of iPSC-derived neural cells in the brain of a non-human primate.

Morizane A, Doi D, Kikuchi T, Okita K, Hotta A, Kawasaki T, Hayashi T, Onoe H, Shiina T, Yamanaka S, Takahashi J. Morizane A, et al. Among authors: hotta a. Stem Cell Reports. 2013 Sep 26;1(4):283-92. doi: 10.1016/j.stemcr.2013.08.007. eCollection 2013. Stem Cell Reports. 2013. PMID: 24319664 Free PMC article.

3

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors.

Oshima K, Saiki N, Tanaka M, Imamura H, Niwa A, Tanimura A, Nagahashi A, Hirayama A, Okita K, Hotta A, Kitayama S, Osawa M, Kaneko S, Watanabe A, Asaka I, Fujibuchi W, Imai K, Yabe H, Kamachi Y, Hara J, Kojima S, Tomita M, Soga T, Noma T, Nonoyama S, Nakahata T, Saito MK. Oshima K, et al. Among authors: hotta a. Biochem Biophys Res Commun. 2018 Mar 4;497(2):719-725. doi: 10.1016/j.bbrc.2018.02.139. Epub 2018 Feb 17. Biochem Biophys Res Commun. 2018. PMID: 29462620 Free article.

4

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs.

Ikeda T, Hikichi T, Miura H, Shibata H, Mitsunaga K, Yamada Y, Woltjen K, Miyamoto K, Hiratani I, Yamada Y, Hotta A, Yamamoto T, Okita K, Masui S. Ikeda T, et al. Among authors: hotta a. Nat Commun. 2018 Apr 11;9(1):1387. doi: 10.1038/s41467-018-03748-1. Nat Commun. 2018. PMID: 29643333 Free PMC article.

5

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility.

Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, Ueda T, Gee P, Nishikawa M, Nomura M, Kitaoka F, Takahashi T, Okita K, Yoshida Y, Kaneko S, Hotta A. Xu H, et al. Among authors: hotta a. Cell Stem Cell. 2019 Apr 4;24(4):566-578.e7. doi: 10.1016/j.stem.2019.02.005. Epub 2019 Mar 7. Cell Stem Cell. 2019. PMID: 30853558 Free article.

6

Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping.

Gee P, Lung MSY, Okuzaki Y, Sasakawa N, Iguchi T, Makita Y, Hozumi H, Miura Y, Yang LF, Iwasaki M, Wang XH, Waller MA, Shirai N, Abe YO, Fujita Y, Watanabe K, Kagita A, Iwabuchi KA, Yasuda M, Xu H, Noda T, Komano J, Sakurai H, Inukai N, Hotta A. Gee P, et al. Among authors: hotta a. Nat Commun. 2020 Mar 13;11(1):1334. doi: 10.1038/s41467-020-14957-y. Nat Commun. 2020. PMID: 32170079 Free PMC article.

7

PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids.

Kuraoka S, Tanigawa S, Taguchi A, Hotta A, Nakazato H, Osafune K, Kobayashi A, Nishinakamura R. Kuraoka S, et al. Among authors: hotta a. J Am Soc Nephrol. 2020 Oct;31(10):2355-2371. doi: 10.1681/ASN.2020030378. Epub 2020 Aug 3. J Am Soc Nephrol. 2020. PMID: 32747355 Free PMC article.

8

A novel ADPKD model using kidney organoids derived from disease-specific human iPSCs.

Shimizu T, Mae SI, Araoka T, Okita K, Hotta A, Yamagata K, Osafune K. Shimizu T, et al. Among authors: hotta a. Biochem Biophys Res Commun. 2020 Sep 3;529(4):1186-1194. doi: 10.1016/j.bbrc.2020.06.141. Epub 2020 Aug 4. Biochem Biophys Res Commun. 2020. PMID: 32819584

9

CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells.

Nakanishi-Koakutsu M, Miki K, Naka Y, Sasaki M, Wakimizu T, Napier SC, Okubo C, Narita M, Nishikawa M, Hata R, Chonabayashi K, Hotta A, Imahashi K, Nishimoto T, Yoshida Y. Nakanishi-Koakutsu M, et al. Among authors: hotta a. Commun Biol. 2024 Feb 28;7(1):231. doi: 10.1038/s42003-024-05809-2. Commun Biol. 2024. PMID: 38418926 Free PMC article.

10

Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.

Imamura K, Sahara N, Kanaan NM, Tsukita K, Kondo T, Kutoku Y, Ohsawa Y, Sunada Y, Kawakami K, Hotta A, Yawata S, Watanabe D, Hasegawa M, Trojanowski JQ, Lee VM, Suhara T, Higuchi M, Inoue H. Imamura K, et al. Among authors: hotta a. Sci Rep. 2016 Oct 10;6:34904. doi: 10.1038/srep34904. Sci Rep. 2016. PMID: 27721502 Free PMC article.

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