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The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication.
Li J, Gui Q, Liang F-X, Sall J, Zhang Q, Duan Y, Dhabaria A, Askenazi M, Ueberheide B, Stapleford KA, Pagano M. Li J, et al. Among authors: pagano m. J Virol. 2023 Oct 31;97(10):e0050723. doi: 10.1128/jvi.00507-23. Epub 2023 Sep 28. J Virol. 2023. PMID: 37768083 Free PMC article.
Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1.
Lignitto L, LeBoeuf SE, Homer H, Jiang S, Askenazi M, Karakousi TR, Pass HI, Bhutkar AJ, Tsirigos A, Ueberheide B, Sayin VI, Papagiannakopoulos T, Pagano M. Lignitto L, et al. Among authors: pagano m. Cell. 2019 Jul 11;178(2):316-329.e18. doi: 10.1016/j.cell.2019.06.003. Epub 2019 Jun 27. Cell. 2019. PMID: 31257023 Free PMC article.
ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection.
Mena EL, Donahue CJ, Vaites LP, Li J, Rona G, O'Leary C, Lignitto L, Miwatani-Minter B, Paulo JA, Dhabaria A, Ueberheide B, Gygi SP, Pagano M, Harper JW, Davey RA, Elledge SJ. Mena EL, et al. Among authors: pagano m. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2023157118. doi: 10.1073/pnas.2023157118. Proc Natl Acad Sci U S A. 2021. PMID: 33827988 Free PMC article.
D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability.
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M. Rona G, et al. Among authors: pagano m. bioRxiv [Preprint]. 2024 Jan 13:2024.01.12.575420. doi: 10.1101/2024.01.12.575420. bioRxiv. 2024. PMID: 38260436 Free PMC article. Updated. Preprint.
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer.
Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng DH, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, Li F, Li S, Ding H, Hu H, Pan Y, Weerasekara V, Jiang B, Wang ES, Ahearn I, Philips M, Papagiannakopoulos T, Tsirigos A, Rothenberg E, Gainor J, Freeman GJ, Rudin CM, Gray NS, Hammerman PS, Pagano M, Heymach JV, Perou CM, Bardeesy N, Wong KK. Deng J, et al. Among authors: pagano m. Nat Cancer. 2021 May;2(5):503-514. doi: 10.1038/s43018-021-00208-6. Epub 2021 May 17. Nat Cancer. 2021. PMID: 34142094 Free PMC article. No abstract available.
1,054 results