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Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, sensitizes cancer cells to VSVΔ51 oncolytic virotherapy.
Wong B, Bergeron A, Maznyi G, Ng K, Jirovec A, Birdi HK, Serrano D, Spinelli M, Thomson M, Taha Z, Alwithenani A, Chen A, Lorimer I, Vanderhyden B, Arulanandam R, Diallo JS. Wong B, et al. Among authors: lorimer i. Mol Ther. 2023 Nov 1;31(11):3176-3192. doi: 10.1016/j.ymthe.2023.09.017. Epub 2023 Sep 27. Mol Ther. 2023. PMID: 37766429
Engineered cells as glioblastoma therapeutics.
Ramanathan A, Lorimer IAJ. Ramanathan A, et al. Among authors: lorimer iaj. Cancer Gene Ther. 2022 Feb;29(2):156-166. doi: 10.1038/s41417-021-00320-w. Epub 2021 Mar 22. Cancer Gene Ther. 2022. PMID: 33753869 Free PMC article. Review.
Engineering PTEN-L for Cell-Mediated Delivery.
Lavictoire SJ, Gont A, Julian LM, Stanford WL, Vlasschaert C, Gray DA, Jomaa D, Lorimer IAJ. Lavictoire SJ, et al. Among authors: lorimer iaj. Mol Ther Methods Clin Dev. 2017 Nov 21;9:12-22. doi: 10.1016/j.omtm.2017.11.006. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2017. PMID: 29255742 Free PMC article.
Coordination of glioblastoma cell motility by PKCι.
Baldwin RM, Barrett GM, Parolin DA, Gillies JK, Paget JA, Lavictoire SJ, Gray DA, Lorimer IA. Baldwin RM, et al. Mol Cancer. 2010 Sep 3;9:233. doi: 10.1186/1476-4598-9-233. Mol Cancer. 2010. PMID: 20815904 Free PMC article.
Repression of cancer cell senescence by PKCι.
Paget JA, Restall IJ, Daneshmand M, Mersereau JA, Simard MA, Parolin DA, Lavictoire SJ, Amin MS, Islam S, Lorimer IA. Paget JA, et al. Among authors: lorimer ia. Oncogene. 2012 Aug 2;31(31):3584-96. doi: 10.1038/onc.2011.524. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120720
62 results