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B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.
González-Ruiz V, Pascua I, Fernández-Marcelo T, Ribelles P, Bianchini G, Sridharan V, Iniesta P, Ramos MT, Olives AI, Martín MA, Menéndez JC. González-Ruiz V, et al. Among authors: menendez jc. PLoS One. 2014 May 15;9(5):e95998. doi: 10.1371/journal.pone.0095998. eCollection 2014. PLoS One. 2014. PMID: 24830682 Free PMC article.
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases.
Staderini M, Aulić S, Bartolini M, Tran HN, González-Ruiz V, Pérez DI, Cabezas N, Martínez A, Martín MA, Andrisano V, Legname G, Menéndez JC, Bolognesi ML. Staderini M, et al. Among authors: menendez jc. ACS Med Chem Lett. 2012 Dec 28;4(2):225-9. doi: 10.1021/ml3003605. eCollection 2013 Feb 14. ACS Med Chem Lett. 2012. PMID: 24900645 Free PMC article.
Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC. De Petrocellis L, et al. Among authors: menendez jc. J Med Chem. 2016 Jun 23;59(12):5661-83. doi: 10.1021/acs.jmedchem.5b01448. Epub 2016 Jun 14. J Med Chem. 2016. PMID: 27232526
Antioxidants as Molecular Probes: Structurally Novel Dihydro-m-Terphenyls as Turn-On Fluorescence Chemodosimeters for Biologically Relevant Oxidants.
González-Ruiz V, Rajesh J, Olives AI, Rocchi D, Gómez-Carpintero J, González JF, Sridharan V, Martín MA, Menéndez JC. González-Ruiz V, et al. Among authors: menendez jc. Antioxidants (Basel). 2020 Jul 10;9(7):605. doi: 10.3390/antiox9070605. Antioxidants (Basel). 2020. PMID: 32664230 Free PMC article.
126 results