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Interaction of ALK Inhibitors with Polyspecific Organic Cation Transporters and the Impact of Substrate-Dependent Inhibition on the Prediction of Drug-Drug Interactions.
Pharmaceutics. 2023 Sep 13;15(9):2312. doi: 10.3390/pharmaceutics15092312.
Pharmaceutics. 2023.
PMID: 37765282
Free PMC article.
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Characterization of Meta-Iodobenzylguanidine (mIBG) Transport by Polyspecific Organic Cation Transporters: Implication for mIBG Therapy.
López Quiñones AJ, Wagner DJ, Wang J.
López Quiñones AJ, et al.
Mol Pharmacol. 2020 Aug;98(2):109-119. doi: 10.1124/mol.120.119495. Epub 2020 Jun 2.
Mol Pharmacol. 2020.
PMID: 32487736
Free PMC article.
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Clinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-Iodobenzylguanidine (mIBG).
Lopez Quiñones AJ, Vieira LS, Wang J.
Lopez Quiñones AJ, et al.
Drug Metab Dispos. 2022 Feb 22;50(9):1218-27. doi: 10.1124/dmd.121.000707. Online ahead of print.
Drug Metab Dispos. 2022.
PMID: 35197314
Free PMC article.
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The Plasma Membrane Monoamine Transporter is Highly Expressed in Neuroblastoma and Functions as an mIBG Transporter.
Vieira LS, Zhang Y, López Quiñones AJ, Hu T, Singh DK, Stevens J, Prasad B, Park JR, Wang J.
Vieira LS, et al. Among authors: lopez quinones aj.
J Pharmacol Exp Ther. 2023 Dec;387(3):239-248. doi: 10.1124/jpet.123.001672. Epub 2023 Aug 4.
J Pharmacol Exp Ther. 2023.
PMID: 37541765
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Development and validation of a LC-MS/MS method for in vivo quantification of meta-iodobenzylguanidine (mIBG).
López Quiñones AJ, Shireman LM, Wang J.
López Quiñones AJ, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Sep 1;1181:122927. doi: 10.1016/j.jchromb.2021.122927. Epub 2021 Sep 3.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021.
PMID: 34530306
Free PMC article.
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Cardiac Uptake of the Adrenergic Imaging Agent meta-Iodobenzylguanidine (mIBG) is Mediated by Organic Cation Transporter 3 (Oct3).
Lopez Quiñones AJ, Vieira LS, Wang J.
Lopez Quiñones AJ, et al.
Drug Metab Dispos. 2024 May 29:DMD-AR-2024-001709. doi: 10.1124/dmd.124.001709. Online ahead of print.
Drug Metab Dispos. 2024.
PMID: 38811159
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