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Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling.
Pathogens. 2023 Sep 18;12(9):1171. doi: 10.3390/pathogens12091171.
Pathogens. 2023.
PMID: 37764979
Free PMC article.
Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores.
Fontes FL, Rooker SA, Lynn-Barbe JK, Lyons MA, Crans DC, Crick DC.
Fontes FL, et al. Among authors: lynn barbe jk.
Front Mol Biosci. 2024 Feb 13;11:1350699. doi: 10.3389/fmolb.2024.1350699. eCollection 2024.
Front Mol Biosci. 2024.
PMID: 38414662
Free PMC article.
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