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PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas.
Cubiella T, Celada L, San-Juan-Guardado J, Rodríguez-Aguilar R, Suárez-Priede Á, Poch M, Dominguez F, Fernández-Vega I, Montero-Pavón P, Fraga MF, Nakatani Y, Takata S, Yachida S, Valdés N, Chiara MD. Cubiella T, et al. Among authors: fraga mf. J Pathol. 2024 May 25. doi: 10.1002/path.6291. Online ahead of print. J Pathol. 2024. PMID: 38795318
A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma.
Rey V, Tornín J, Alba-Linares JJ, Robledo C, Murillo D, Rodríguez A, Gallego B, Huergo C, Viera C, Braña A, Astudillo A, Heymann D, Szuhai K, Bovée JVMG, Fernández AF, Fraga MF, Alonso J, Rodríguez R. Rey V, et al. Among authors: fraga mf. EBioMedicine. 2024 Apr;102:105090. doi: 10.1016/j.ebiom.2024.105090. Epub 2024 Mar 27. EBioMedicine. 2024. PMID: 38547578 Free PMC article.
A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin.
González J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Espinosa-Alcantud M, Fernandez AF, Brown JP, Ausió J, Vazquez BN, Singh PB, Fraga MF, Vaquero A. González J, et al. Among authors: fraga mf. Front Cell Dev Biol. 2023 Nov 9;11:1293122. doi: 10.3389/fcell.2023.1293122. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020886 Free PMC article.
A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.
Bueno C, Torres-Ruiz R, Velasco-Hernandez T, Molina O, Petazzi P, Martinez A, Rodriguez V, Vinyoles M, Cantilena S, Williams O, Vega-Garcia N, Rodriguez-Perales S, Segovia JC, Quintana-Bustamante O, Roy A, Meyer C, Marschalek R, Smith AL, Milne TA, Fraga MF, Tejedor JR, Menéndez P. Bueno C, et al. Among authors: fraga mf. Blood. 2023 Nov 16;142(20):1752-1756. doi: 10.1182/blood.2023020858. Blood. 2023. PMID: 37756522
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Tejedor JR, Peñarroya A, Gancedo-Verdejo J, Santamarina-Ojeda P, Pérez RF, López-Tamargo S, Díez-Borge A, Alba-Linares JJ, González-Del-Rey N, Urdinguio RG, Mangas C, Roberti A, López V, Morales-Ruiz T, Ariza RR, Roldán-Arjona T, Meijón M, Valledor L, Cañal MJ, Fernández-Martínez D, Fernández-Hevia M, Jiménez-Fonseca P, García-Flórez LJ, Fernández AF, Fraga MF. Tejedor JR, et al. Among authors: fraga mf. Clin Epigenetics. 2023 Aug 24;15(1):133. doi: 10.1186/s13148-023-01546-1. Clin Epigenetics. 2023. PMID: 37612734 Free PMC article.
DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype.
Cuesta-Borràs E, Salvans C, Arqués O, Chicote I, Ramírez L, Cabellos L, Martínez-Quintanilla J, Mur-Espinosa A, García-Álvarez A, Hernando J, Tejedor JR, Mirallas O, Élez E, Fraga MF, Tabernero J, Nuciforo P, Capdevila J, Palmer HG, Puig I. Cuesta-Borràs E, et al. Among authors: fraga mf. Cell Rep. 2023 Aug 29;42(8):112927. doi: 10.1016/j.celrep.2023.112927. Epub 2023 Aug 1. Cell Rep. 2023. PMID: 37537841 Free article.
249 results