Liu J - Search Results

1

Collective Synthesis of Sarpagine and Macroline Alkaloid-Inspired Compounds.

Aoyama H, Davies C, Liu J, Pahl A, Kirchhoff JL, Scheel R, Sievers S, Strohmann C, Grigalunas M, Waldmann H. Aoyama H, et al. Among authors: liu j. Chemistry. 2024 Jan 22;30(5):e202303027. doi: 10.1002/chem.202303027. Epub 2023 Nov 29. Chemistry. 2024. PMID: 37755456

2

Guided by evolution: from biology oriented synthesis to pseudo natural products.

Cremosnik GS, Liu J, Waldmann H. Cremosnik GS, et al. Among authors: liu j. Nat Prod Rep. 2020 Nov 18;37(11):1497-1510. doi: 10.1039/d0np00015a. Nat Prod Rep. 2020. PMID: 33020792 Review.

3

Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products.

Liu J, Cremosnik GS, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H. Liu J, et al. Angew Chem Int Ed Engl. 2021 Feb 23;60(9):4648-4656. doi: 10.1002/anie.202013731. Epub 2021 Jan 12. Angew Chem Int Ed Engl. 2021. PMID: 33200868 Free PMC article.

4

Combination of Pseudo-Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo-Sesquiterpenoid Alkaloids.

Liu J, Flegel J, Otte F, Pahl A, Sievers S, Strohmann C, Waldmann H. Liu J, et al. Angew Chem Int Ed Engl. 2021 Sep 20;60(39):21384-21395. doi: 10.1002/anie.202106654. Epub 2021 Aug 19. Angew Chem Int Ed Engl. 2021. PMID: 34297473 Free PMC article.

5

Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay.

Schölermann B, Bonowski J, Grigalunas M, Burhop A, Xie Y, Hoock JGF, Liu J, Dow M, Nelson A, Nowak C, Pahl A, Sievers S, Ziegler S. Schölermann B, et al. Among authors: liu j. Chembiochem. 2022 Nov 18;23(22):e202200475. doi: 10.1002/cbic.202200475. Epub 2022 Oct 13. Chembiochem. 2022. PMID: 36134475 Free PMC article.

6

Morphological Profiling Identifies the Motor Protein Eg5 as Cellular Target of Spirooxindoles.

Liu J, Mallick S, Xie Y, Grassin C, Lucas B, Schölermann B, Pahl A, Scheel R, Strohmann C, Protzel C, Berg T, Merten C, Ziegler S, Waldmann H. Liu J, et al. Angew Chem Int Ed Engl. 2023 May 15;62(21):e202301955. doi: 10.1002/anie.202301955. Epub 2023 Apr 18. Angew Chem Int Ed Engl. 2023. PMID: 36929571

7

A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway.

Liu J, Zhang R, Mallick S, Patil S, Wientjens C, Flegel J, Krupp A, Strohmann C, Grassin C, Merten C, Pahl A, Grigalunas M, Waldmann H. Liu J, et al. Chem Sci. 2023 Jun 21;14(29):7936-7943. doi: 10.1039/d3sc01240a. eCollection 2023 Jul 26. Chem Sci. 2023. PMID: 37502335 Free PMC article.

8

Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space.

Xie J, Pahl A, Krzyzanowski A, Krupp A, Liu J, Koska S, Schölermann B, Zhang R, Bonowski J, Sievers S, Strohmann C, Ziegler S, Grigalunas M, Waldmann H. Xie J, et al. Among authors: liu j. Angew Chem Int Ed Engl. 2023 Nov 27;62(48):e202310222. doi: 10.1002/anie.202310222. Epub 2023 Oct 24. Angew Chem Int Ed Engl. 2023. PMID: 37818743

9

A divergent intermediate strategy yields biologically diverse pseudo-natural products.

Bag S, Liu J, Patil S, Bonowski J, Koska S, Schölermann B, Zhang R, Wang L, Pahl A, Sievers S, Brieger L, Strohmann C, Ziegler S, Grigalunas M, Waldmann H. Bag S, et al. Among authors: liu j. Nat Chem. 2024 Feb 16. doi: 10.1038/s41557-024-01458-4. Online ahead of print. Nat Chem. 2024. PMID: 38365941

10

Illuminating Dark Chemical Matter Using the Cell Painting Assay.

Pahl A, Liu J, Patil S, Rezaei Adariani S, Schölermann B, Warmers J, Bonowski J, Koska S, Akbulut Y, Seitz C, Sievers S, Ziegler S, Waldmann H. Pahl A, et al. Among authors: liu j. J Med Chem. 2024 Apr 30. doi: 10.1021/acs.jmedchem.4c00160. Online ahead of print. J Med Chem. 2024. PMID: 38687818

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