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Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation.
Front Immunol. 2023 Sep 7;14:1231700. doi: 10.3389/fimmu.2023.1231700. eCollection 2023.
Front Immunol. 2023.
PMID: 37744380
Free PMC article.
Nix-Mediated Mitophagy Modulates Mitochondrial Damage During Intestinal Inflammation.
Vincent G, Novak EA, Siow VS, Cunningham KE, Griffith BD, Comerford TE, Mentrup HL, Stolz DB, Loughran P, Ranganathan S, Mollen KP.
Vincent G, et al. Among authors: mentrup hl.
Antioxid Redox Signal. 2020 Jul 1;33(1):1-19. doi: 10.1089/ars.2018.7702. Epub 2020 Mar 31.
Antioxid Redox Signal. 2020.
PMID: 32103677
Free PMC article.
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Cyclic GMP-AMP synthase contributes to epithelial homeostasis in intestinal inflammation via Beclin-1-mediated autophagy.
Khan S, Mentrup HL, Novak EA, Siow VS, Wang Q, Crawford EC, Schneider C, Comerford TE 4th, Firek B, Rogers MB, Loughran P, Morowitz MJ, Mollen KP.
Khan S, et al. Among authors: mentrup hl.
FASEB J. 2022 May;36(5):e22282. doi: 10.1096/fj.202200138R.
FASEB J. 2022.
PMID: 35344224
Free PMC article.
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Studying the Epithelial Effects of Intestinal Inflammation In Vitro on Established Murine Colonoids.
Crawford E, Mentrup HL, Novak EA, Mollen KP.
Crawford E, et al. Among authors: mentrup hl.
J Vis Exp. 2023 Jun 2;(196):10.3791/64804. doi: 10.3791/64804.
J Vis Exp. 2023.
PMID: 37335108
Free PMC article.
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Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage.
Burr AHP, Ji J, Ozler K, Mentrup HL, Eskiocak O, Yueh B, Cumberland R, Menk AV, Rittenhouse N, Marshall CW, Chiaranunt P, Zhang X, Mullinax L, Overacre-Delgoffe A, Cooper VS, Poholek AC, Delgoffe GM, Mollen KP, Beyaz S, Hand TW.
Burr AHP, et al. Among authors: mentrup hl.
Cell Mol Gastroenterol Hepatol. 2023;16(2):287-316. doi: 10.1016/j.jcmgh.2023.05.001. Epub 2023 May 11.
Cell Mol Gastroenterol Hepatol. 2023.
PMID: 37172822
Free PMC article.
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Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death.
Lamade AM, Wu L, Dar HH, Mentrup HL, Shrivastava IH, Epperly MW, St Croix CM, Tyurina YY, Anthonymuthu TS, Yang Q, Kapralov AA, Huang Z, Mao G, Amoscato AA, Hier ZE, Artyukhova MA, Shurin G, Rosenbaum JC, Gough PJ, Bertin J, VanDemark AP, Watkins SC, Mollen KP, Bahar I, Greenberger JS, Kagan VE, Whalen MJ, Bayır H.
Lamade AM, et al. Among authors: mentrup hl.
Redox Biol. 2022 Apr;50:102232. doi: 10.1016/j.redox.2022.102232. Epub 2022 Jan 10.
Redox Biol. 2022.
PMID: 35101798
Free PMC article.
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The ubiquitin ligase ITCH coordinates small intestinal epithelial homeostasis by modulating cell proliferation, differentiation, and migration.
Mentrup HL, Hartman A, Thames EL, Basheer WA, Matesic LE.
Mentrup HL, et al.
Differentiation. 2018 Jan-Feb;99:51-61. doi: 10.1016/j.diff.2017.12.003. Epub 2017 Dec 15.
Differentiation. 2018.
PMID: 29309986
Free PMC article.
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Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.
Basheer WA, Harris BS, Mentrup HL, Abreha M, Thames EL, Lea JB, Swing DA, Copeland NG, Jenkins NA, Price RL, Matesic LE.
Basheer WA, et al. Among authors: mentrup hl.
J Mol Cell Cardiol. 2015 Nov;88:1-13. doi: 10.1016/j.yjmcc.2015.09.004. Epub 2015 Sep 16.
J Mol Cell Cardiol. 2015.
PMID: 26386426
Free PMC article.
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