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A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration.
Na D, Lim DH, Hong JS, Lee HM, Cho D, Yu MS, Shaker B, Ren J, Lee B, Song JG, Oh Y, Lee K, Oh KS, Lee MY, Choi MS, Choi HS, Kim YH, Bui JM, Lee K, Kim HW, Lee YS, Gsponer J. Na D, et al. Among authors: gsponer j. Mol Syst Biol. 2023 Dec 6;19(12):e11801. doi: 10.15252/msb.202311801. Epub 2023 Nov 20. Mol Syst Biol. 2023. PMID: 37984409 Free PMC article.
Shift of the insoluble content of the proteome in the aging mouse brain.
Molzahn C, Kuechler ER, Zemlyankina I, Nierves L, Ali T, Cole G, Wang J, Albu RF, Zhu M, Cashman NR, Gilch S, Karsan A, Lange PF, Gsponer J, Mayor T. Molzahn C, et al. Among authors: gsponer j. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2310057120. doi: 10.1073/pnas.2310057120. Epub 2023 Oct 31. Proc Natl Acad Sci U S A. 2023. PMID: 37906643 Free PMC article.
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, Otten EG, Panda PK, Lara-Reyna S, Korsgen ME, Kauffman KJ, Huerta-Uribe A, Zatyka M, Silva LFSE, Torresi J, Zhang S, Hughes GW, Ward C, Kuechler ER, Cartwright D, Trushin S, Trushina E, Sahay G, Buganim Y, Lavery GG, Gsponer J, Anderson DG, Frickel EM, Rosenstock TR, Barrett T, Maddocks ODK, Tennant DA, Wang H, Jaenisch R, Korolchuk VI, Sarkar S. Sun C, et al. Among authors: gsponer j. Cell Rep. 2023 May 30;42(5):112372. doi: 10.1016/j.celrep.2023.112372. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086404 Free PMC article.
Phase Separation in Biology and Disease; Current Perspectives and Open Questions.
Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea DM, Mueller-Cajar O, Portz B, Reilly JF, Reinkemeier CD, Sabari BR, Sanulli S, Shorter J, Sontag E, Strader L, Stachowiak J, Weber SC, White M, Zhang H, Zweckstetter M, Elbaum-Garfinkle S, Kriwacki R. Boeynaems S, et al. Among authors: gsponer j. J Mol Biol. 2023 Mar 1;435(5):167971. doi: 10.1016/j.jmb.2023.167971. Epub 2023 Jan 21. J Mol Biol. 2023. PMID: 36690068 Free PMC article.
103 results