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Targeting SARS-CoV-2 Main Protease (MPro) with Kinase Inhibitors: A Promising Approach for Discovering Antiviral and Anti-inflammatory Molecules against SARS-CoV-2.
Anton DB, Galvez Bulhões Pedreira J, Zvirtes ML, Laufer SA, Ducati RG, Goettert M, Saraiva Macedo Timmers LF. Anton DB, et al. Among authors: saraiva macedo timmers lf. J Chem Inf Model. 2023 Jul 10;63(13):4138-4146. doi: 10.1021/acs.jcim.3c00324. Epub 2023 Jun 17. J Chem Inf Model. 2023. PMID: 37329322
A network flow approach to predict protein targets and flavonoid backbones to treat respiratory syncytial virus infection.
Vargas JE, Puga R, de Faria Poloni J, Saraiva Macedo Timmers LF, Porto BN, Norberto de Souza O, Bonatto D, Condessa Pitrez PM, Tetelbom Stein R. Vargas JE, et al. Among authors: saraiva macedo timmers lf. Biomed Res Int. 2015;2015:301635. doi: 10.1155/2015/301635. Epub 2015 Mar 22. Biomed Res Int. 2015. PMID: 25879022 Free PMC article.
Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A.
Hettich J, Ryan SD, de Souza ON, Saraiva Macedo Timmers LF, Tsai S, Atai NA, da Hora CC, Zhang X, Kothary R, Snapp E, Ericsson M, Grundmann K, Breakefield XO, Nery FC. Hettich J, et al. Among authors: saraiva macedo timmers lf. Hum Mutat. 2014 Sep;35(9):1101-13. doi: 10.1002/humu.22602. Epub 2014 Jul 17. Hum Mutat. 2014. PMID: 24930953 Free PMC article.
Biochemical characterization of recombinant nucleoside hydrolase from Mycobacterium tuberculosis H37Rv.
Wink PL, Sanchez Quitian ZA, Rosado LA, Rodrigues Vda S Jr, Petersen GO, Lorenzini DM, Lipinski-Paes T, Saraiva Macedo Timmers LF, de Souza ON, Basso LA, Santos DS. Wink PL, et al. Among authors: saraiva macedo timmers lf. Arch Biochem Biophys. 2013 Oct 15;538(2):80-94. doi: 10.1016/j.abb.2013.08.011. Epub 2013 Aug 26. Arch Biochem Biophys. 2013. PMID: 23988349 Free article.