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Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.
Oh S, Park Y, Engelhart CA, Wallach JB, Schnappinger D, Arora K, Manikkam M, Gac B, Wang H, Murgolo N, Olsen DB, Goodwin M, Sutphin M, Weiner DM, Via LE, Boshoff HIM, Barry CE 3rd. Oh S, et al. J Med Chem. 2018 Nov 21;61(22):9952-9965. doi: 10.1021/acs.jmedchem.8b00883. Epub 2018 Nov 5. J Med Chem. 2018. PMID: 30350998 Free PMC article.
Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis.
Park Y, Ahn YM, Jonnala S, Oh S, Fisher JM, Goodwin MB, Ioerger TR, Via LE, Bayliss T, Green SR, Ray PC, Wyatt PG, Barry CE 3rd, Boshoff HI. Park Y, et al. Among authors: oh s. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01006-19. doi: 10.1128/AAC.01006-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31383669 Free PMC article.
MAIT cell-directed therapy of Mycobacterium tuberculosis infection.
Sakai S, Kauffman KD, Oh S, Nelson CE, Barry CE 3rd, Barber DL. Sakai S, et al. Among authors: oh s. Mucosal Immunol. 2021 Jan;14(1):199-208. doi: 10.1038/s41385-020-0332-4. Epub 2020 Aug 18. Mucosal Immunol. 2021. PMID: 32811991 Free PMC article.
Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis.
Libardo MDJ, Duncombe CJ, Green SR, Wyatt PG, Thompson S, Ray PC, Ioerger TR, Oh S, Goodwin MB, Boshoff HIM, Barry CE 3rd. Libardo MDJ, et al. Among authors: oh s. Cell Chem Biol. 2021 Aug 19;28(8):1180-1191.e20. doi: 10.1016/j.chembiol.2021.02.023. Epub 2021 Mar 24. Cell Chem Biol. 2021. PMID: 33765439 Free PMC article.
Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response.
Ruf B, Catania VV, Wabitsch S, Ma C, Diggs LP, Zhang Q, Heinrich B, Subramanyam V, Cui LL, Pouzolles M, Evans CN, Chari R, Sakai S, Oh S, Barry CE 3rd, Barber DL, Greten TF. Ruf B, et al. Among authors: oh s. Cancer Immunol Res. 2021 Sep;9(9):1024-1034. doi: 10.1158/2326-6066.CIR-20-0925. Epub 2021 Jun 30. Cancer Immunol Res. 2021. PMID: 34193462 Free PMC article.
Chemical approaches to unraveling the biology of mycobacteria.
Finin P, Khan RMN, Oh S, Boshoff HIM, Barry CE 3rd. Finin P, et al. Among authors: oh s. Cell Chem Biol. 2023 May 18;30(5):420-435. doi: 10.1016/j.chembiol.2023.04.014. Cell Chem Biol. 2023. PMID: 37207631 Free PMC article. Review.
15,026 results
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