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PET reporter systems for the brain.
Nerella SG, Michaelides M, Minamimoto T, Innis RB, Pike VW, Eldridge MAG. Nerella SG, et al. Among authors: eldridge mag. Trends Neurosci. 2023 Nov;46(11):941-952. doi: 10.1016/j.tins.2023.08.007. Epub 2023 Sep 19. Trends Neurosci. 2023. PMID: 37734962 Review.
PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation.
Nagai Y, Kikuchi E, Lerchner W, Inoue KI, Ji B, Eldridge MA, Kaneko H, Kimura Y, Oh-Nishi A, Hori Y, Kato Y, Hirabayashi T, Fujimoto A, Kumata K, Zhang MR, Aoki I, Suhara T, Higuchi M, Takada M, Richmond BJ, Minamimoto T. Nagai Y, et al. Nat Commun. 2016 Dec 6;7:13605. doi: 10.1038/ncomms13605. Nat Commun. 2016. PMID: 27922009 Free PMC article.
High-potency ligands for DREADD imaging and activation in rodents and monkeys.
Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M. Bonaventura J, et al. Among authors: eldridge mag. Nat Commun. 2019 Oct 11;10(1):4627. doi: 10.1038/s41467-019-12236-z. Nat Commun. 2019. PMID: 31604917 Free PMC article.
PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study.
Shrestha S, Kim MJ, Eldridge M, Lehmann ML, Frankland M, Liow JS, Yu ZX, Cortes-Salva M, Telu S, Henter ID, Gallagher E, Lee JH, Fredericks JM, Poffenberger C, Tye G, Ruiz-Perdomo Y, Anaya FJ, Montero Santamaria JA, Gladding RL, Zoghbi SS, Fujita M, Katz JD, Pike VW, Innis RB. Shrestha S, et al. J Neuroinflammation. 2020 May 2;17(1):140. doi: 10.1186/s12974-020-01804-6. J Neuroinflammation. 2020. PMID: 32359360 Free PMC article. Clinical Trial.
[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain.
Yan X, Telu S, Dick RM, Liow JS, Zanotti-Fregonara P, Morse CL, Manly LS, Gladding RL, Shrestha S, Lerchner W, Nagai Y, Minamimoto T, Zoghbi SS, Innis RB, Pike VW, Richmond BJ, Eldridge MA. Yan X, et al. J Cereb Blood Flow Metab. 2021 Oct;41(10):2571-2582. doi: 10.1177/0271678X211007949. Epub 2021 Apr 14. J Cereb Blood Flow Metab. 2021. PMID: 33853405 Free PMC article.
Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action.
Oyama K, Hori Y, Mimura K, Nagai Y, Eldridge MAG, Saunders RC, Miyakawa N, Hirabayashi T, Hori Y, Inoue KI, Suhara T, Takada M, Higuchi M, Richmond BJ, Minamimoto T. Oyama K, et al. Among authors: eldridge mag. J Neurosci. 2022 Aug 10;42(32):6267-6275. doi: 10.1523/JNEUROSCI.0229-22.2022. Epub 2022 Jul 6. J Neurosci. 2022. PMID: 35794012 Free PMC article.
Distinct roles of monkey OFC-subcortical pathways in adaptive behavior.
Oyama K, Majima K, Nagai Y, Hori Y, Hirabayashi T, Eldridge MAG, Mimura K, Miyakawa N, Fujimoto A, Hori Y, Iwaoki H, Inoue KI, Saunders RC, Takada M, Yahata N, Higuchi M, Richmond BJ, Minamimoto T. Oyama K, et al. Among authors: eldridge mag. bioRxiv [Preprint]. 2023 Nov 17:2023.11.17.567492. doi: 10.1101/2023.11.17.567492. bioRxiv. 2023. PMID: 38076986 Free PMC article. Preprint.
Resisting the Urge to Act: DREADDs Modifying Habits.
Eldridge MAG, Richmond BJ. Eldridge MAG, et al. Trends Neurosci. 2017 Feb;40(2):61-62. doi: 10.1016/j.tins.2016.12.002. Epub 2017 Jan 16. Trends Neurosci. 2017. PMID: 28104285 Free PMC article. Review.
34 results