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Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade.
Cancer Discov. 2023 Dec 12;13(12):2566-2583. doi: 10.1158/2159-8290.CD-22-1301.
Cancer Discov. 2023.
PMID: 37728660
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity.
LaFleur MW, Nguyen TH, Coxe MA, Miller BC, Yates KB, Gillis JE, Sen DR, Gaudiano EF, Al Abosy R, Freeman GJ, Haining WN, Sharpe AH.
LaFleur MW, et al. Among authors: gaudiano ef.
Nat Immunol. 2019 Oct;20(10):1335-1347. doi: 10.1038/s41590-019-0480-4. Epub 2019 Sep 16.
Nat Immunol. 2019.
PMID: 31527834
Free PMC article.
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Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells.
Drijvers JM, Gillis JE, Muijlwijk T, Nguyen TH, Gaudiano EF, Harris IS, LaFleur MW, Ringel AE, Yao CH, Kurmi K, Juneja VR, Trombley JD, Haigis MC, Sharpe AH.
Drijvers JM, et al. Among authors: gaudiano ef.
Cancer Immunol Res. 2021 Feb;9(2):184-199. doi: 10.1158/2326-6066.CIR-20-0384. Epub 2020 Dec 4.
Cancer Immunol Res. 2021.
PMID: 33277233
Free PMC article.
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Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation.
Boytz R, Seitz S, Gaudiano E, Patten JJ, Keiser PT, Connor JH, Sharpe AH, Davey RA.
Boytz R, et al.
Viruses. 2022 Dec 23;15(1):43. doi: 10.3390/v15010043.
Viruses. 2022.
PMID: 36680083
Free PMC article.
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TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.
Zhang H, Kozono DE, O'Connor KW, Vidal-Cardenas S, Rousseau A, Hamilton A, Moreau L, Gaudiano EF, Greenberger J, Bagby G, Soulier J, Grompe M, Parmar K, D'Andrea AD.
Zhang H, et al. Among authors: gaudiano ef.
Cell Stem Cell. 2016 May 5;18(5):668-81. doi: 10.1016/j.stem.2016.03.002. Epub 2016 Mar 24.
Cell Stem Cell. 2016.
PMID: 27053300
Free PMC article.
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USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.
Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD.
Lim KS, et al. Among authors: gaudiano ef.
Mol Cell. 2018 Dec 20;72(6):925-941.e4. doi: 10.1016/j.molcel.2018.10.045.
Mol Cell. 2018.
PMID: 30576655
Free PMC article.
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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.
Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A.
Davis MI, et al. Among authors: gaudiano ef.
J Biol Chem. 2016 Nov 18;291(47):24628-24640. doi: 10.1074/jbc.M116.738567. Epub 2016 Sep 28.
J Biol Chem. 2016.
PMID: 27681596
Free PMC article.
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Serum microRNAs are early indicators of survival after radiation-induced hematopoietic injury.
Acharya SS, Fendler W, Watson J, Hamilton A, Pan Y, Gaudiano E, Moskwa P, Bhanja P, Saha S, Guha C, Parmar K, Chowdhury D.
Acharya SS, et al.
Sci Transl Med. 2015 May 13;7(287):287ra69. doi: 10.1126/scitranslmed.aaa6593.
Sci Transl Med. 2015.
PMID: 25972001
Free PMC article.
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