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C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer's disease.
Gomez-Arboledas A, Carvalho K, Balderrama-Gutierrez G, Chu SH, Liang HY, Schartz ND, Selvan P, Petrisko TJ, Pan MA, Mortazavi A, Tenner AJ. Gomez-Arboledas A, et al. Among authors: petrisko tj. Acta Neuropathol Commun. 2022 Aug 17;10(1):116. doi: 10.1186/s40478-022-01416-6. Acta Neuropathol Commun. 2022. PMID: 35978440 Free PMC article.
Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression.
Carvalho K, Schartz ND, Balderrama-Gutierrez G, Liang HY, Chu SH, Selvan P, Gomez-Arboledas A, Petrisko TJ, Fonseca MI, Mortazavi A, Tenner AJ. Carvalho K, et al. Among authors: petrisko tj. J Neuroinflammation. 2022 Jul 11;19(1):178. doi: 10.1186/s12974-022-02539-2. J Neuroinflammation. 2022. PMID: 35820938 Free PMC article.