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Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance.
Ito H, Navratilova E, Vagnerova B, Watanabe M, Kopruszinski C, Moreira de Souza LH, Yue X, Ikegami D, Moutal A, Patwardhan A, Khanna R, Yamazaki M, Guerrero M, Rosen H, Roberts E, Neugebauer V, Dodick DW, Porreca F. Ito H, et al. Among authors: roberts e. Brain. 2023 Mar 1;146(3):1186-1199. doi: 10.1093/brain/awac153. Brain. 2023. PMID: 35485490 Free PMC article.
Antagonists of the kappa opioid receptor.
Urbano M, Guerrero M, Rosen H, Roberts E. Urbano M, et al. Among authors: roberts e. Bioorg Med Chem Lett. 2014 May 1;24(9):2021-32. doi: 10.1016/j.bmcl.2014.03.040. Epub 2014 Mar 24. Bioorg Med Chem Lett. 2014. PMID: 24690494 Review.
Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention.
Xie JY, De Felice M, Kopruszinski CM, Eyde N, LaVigne J, Remeniuk B, Hernandez P, Yue X, Goshima N, Ossipov M, King T, Streicher JM, Navratilova E, Dodick D, Rosen H, Roberts E, Porreca F. Xie JY, et al. Among authors: roberts e. Cephalalgia. 2017 Jul;37(8):780-794. doi: 10.1177/0333102417702120. Epub 2017 Apr 4. Cephalalgia. 2017. PMID: 28376659 Free PMC article.
Modulators of the Sphingosine 1-phosphate receptor 1.
Urbano M, Guerrero M, Rosen H, Roberts E. Urbano M, et al. Among authors: roberts e. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6377-89. doi: 10.1016/j.bmcl.2013.09.058. Epub 2013 Sep 29. Bioorg Med Chem Lett. 2013. PMID: 24125884 Free PMC article. Review.
2,157 results