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Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
Johnson M, Bell A, Lauing KL, Ladomersky E, Zhai L, Penco-Campillo M, Shah Y, Mauer E, Xiu J, Nicolaides T, Drumm M, McCortney K, Elemento O, Kim M, Bommi P, Low JT, Memon R, Wu J, Zhao J, Mi X, Glantz MJ, Sengupta S, Castro B, Yamini B, Horbinski C, Baker DJ, Walunas TL, Schiltz GE, Lukas RV, Wainwright DA. Johnson M, et al. Among authors: wu j. Clin Cancer Res. 2023 Dec 1;29(23):4973-4989. doi: 10.1158/1078-0432.CCR-23-0834. Clin Cancer Res. 2023. PMID: 37725593 Free PMC article.
Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017).
Zhai L, Ladomersky E, Lauing KL, Wu M, Scholtens DM, Savoor R, Zhang B, Wu JD, Horbinski C, Lukas RV, Binder DC, Wainwright DA. Zhai L, et al. Oncoimmunology. 2018 Dec 13;8(3):1548242. doi: 10.1080/2162402X.2018.1548242. eCollection 2019. Oncoimmunology. 2018. PMID: 30723577 Free PMC article.
CD73: an emerging checkpoint for cancer immunotherapy.
Chen S, Wainwright DA, Wu JD, Wan Y, Matei DE, Zhang Y, Zhang B. Chen S, et al. Immunotherapy. 2019 Aug;11(11):983-997. doi: 10.2217/imt-2018-0200. Epub 2019 Jun 21. Immunotherapy. 2019. PMID: 31223045 Free PMC article.
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Ladomersky E, Zhai L, Lauing KL, Bell A, Xu J, Kocherginsky M, Zhang B, Wu JD, Podojil JR, Platanias LC, Mochizuki AY, Prins RM, Kumthekar P, Raizer JJ, Dixit K, Lukas RV, Horbinski C, Wei M, Zhou C, Pawelec G, Campisi J, Grohmann U, Prendergast GC, Munn DH, Wainwright DA. Ladomersky E, et al. Among authors: wu jd. Clin Cancer Res. 2020 Oct 1;26(19):5232-5245. doi: 10.1158/1078-0432.CCR-19-3874. Epub 2020 Jun 16. Clin Cancer Res. 2020. PMID: 32546647 Free PMC article.
Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
Zhai L, Bell A, Ladomersky E, Lauing KL, Bollu L, Sosman JA, Zhang B, Wu JD, Miller SD, Meeks JJ, Lukas RV, Wyatt E, Doglio L, Schiltz GE, McCusker RH, Wainwright DA. Zhai L, et al. Among authors: wu jd. Front Immunol. 2020 Jun 16;11:1185. doi: 10.3389/fimmu.2020.01185. eCollection 2020. Front Immunol. 2020. PMID: 32612606 Free PMC article. Review.
Targeting CD73 to augment cancer immunotherapy.
Roh M, Wainwright DA, Wu JD, Wan Y, Zhang B. Roh M, et al. Curr Opin Pharmacol. 2020 Aug;53:66-76. doi: 10.1016/j.coph.2020.07.001. Epub 2020 Aug 7. Curr Opin Pharmacol. 2020. PMID: 32777746 Free PMC article. Review.
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