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Nonclinical safety assessment of an mRNA Covid-19 vaccine candidate following repeated administrations and biodistribution.
J Appl Toxicol. 2024 Mar;44(3):371-390. doi: 10.1002/jat.4548. Epub 2023 Sep 18.
J Appl Toxicol. 2024.
PMID: 37723625
The impact of nucleoside base modification in mRNA vaccine is influenced by the chemistry of its lipid nanoparticle delivery system.
Bernard MC, Bazin E, Petiot N, Lemdani K, Commandeur S, Verdelet C, Margot S, Perkov V, Ripoll M, Garinot M, Ruiz S, Boudet F, Rokbi B, Haensler J.
Bernard MC, et al. Among authors: perkov v.
Mol Ther Nucleic Acids. 2023 May 8;32:794-806. doi: 10.1016/j.omtn.2023.05.004. eCollection 2023 Jun 13.
Mol Ther Nucleic Acids. 2023.
PMID: 37346973
Free PMC article.
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An imidazole modified lipid confers enhanced mRNA-LNP stability and strong immunization properties in mice and non-human primates.
Ripoll M, Bernard MC, Vaure C, Bazin E, Commandeur S, Perkov V, Lemdani K, Nicolaï MC, Bonifassi P, Kichler A, Frisch B, Haensler J.
Ripoll M, et al. Among authors: perkov v.
Biomaterials. 2022 Jul;286:121570. doi: 10.1016/j.biomaterials.2022.121570. Epub 2022 May 7.
Biomaterials. 2022.
PMID: 35576809
Free PMC article.
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