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Page 1
Molecular basis for maternal inheritance of human mitochondrial DNA.
Lee W, Zamudio-Ochoa A, Buchel G, Podlesniy P, Marti Gutierrez N, Puigròs M, Calderon A, Tang HY, Li L, Mikhalchenko A, Koski A, Trullas R, Mitalipov S, Temiakov D. Lee W, et al. Among authors: buchel g. Nat Genet. 2023 Oct;55(10):1632-1639. doi: 10.1038/s41588-023-01505-9. Epub 2023 Sep 18. Nat Genet. 2023. PMID: 37723262 Free PMC article.
Structural basis for DNA proofreading.
Buchel G, Nayak AR, Herbine K, Sarfallah A, Sokolova VO, Zamudio-Ochoa A, Temiakov D. Buchel G, et al. Nat Commun. 2023 Dec 27;14(1):8501. doi: 10.1038/s41467-023-44198-8. Nat Commun. 2023. PMID: 38151585 Free PMC article.
Reproducibility efforts as a teaching tool: A pilot study.
Karathanasis N, Hwang D, Heng V, Abhimannyu R, Slogoff-Sevilla P, Buchel G, Frisbie V, Li P, Kryoneriti D, Rigoutsos I. Karathanasis N, et al. Among authors: buchel g. PLoS Comput Biol. 2022 Nov 10;18(11):e1010615. doi: 10.1371/journal.pcbi.1010615. eCollection 2022 Nov. PLoS Comput Biol. 2022. PMID: 36355750 Free PMC article.
The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex.
Papadopoulos D, Ha SA, Fleischhauer D, Uhl L, Russell TJ, Mikicic I, Schneider K, Brem A, Valanju OR, Cossa G, Gallant P, Schuelein-Voelk C, Maric HM, Beli P, Büchel G, Vos SM, Eilers M. Papadopoulos D, et al. Among authors: buchel g. Mol Cell. 2024 Apr 26:S1097-2765(24)00285-5. doi: 10.1016/j.molcel.2024.04.007. Online ahead of print. Mol Cell. 2024. PMID: 38703770 Free article.
LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma.
Alborzinia H, Chen Z, Yildiz U, Freitas FP, Vogel FCE, Varga JP, Batani J, Bartenhagen C, Schmitz W, Büchel G, Michalke B, Zheng J, Meierjohann S, Girardi E, Espinet E, Flórez AF, Dos Santos AF, Aroua N, Cheytan T, Haenlin J, Schlicker L, Xavier da Silva TN, Przybylla A, Zeisberger P, Superti-Furga G, Eilers M, Conrad M, Fabiano M, Schweizer U, Fischer M, Schulze A, Trumpp A, Friedmann Angeli JP. Alborzinia H, et al. Among authors: buchel g. EMBO Mol Med. 2023 Aug 7;15(8):e18014. doi: 10.15252/emmm.202318014. Epub 2023 Jul 12. EMBO Mol Med. 2023. PMID: 37435859 Free PMC article.
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A. Kalogirou C, et al. Among authors: buchel g. Nat Commun. 2021 Aug 20;12(1):5066. doi: 10.1038/s41467-021-25325-9. Nat Commun. 2021. PMID: 34417456 Free PMC article.
Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma.
Roeschert I, Poon E, Henssen AG, Garcia HD, Gatti M, Giansanti C, Jamin Y, Ade CP, Gallant P, Schülein-Völk C, Beli P, Richards M, Rosenfeldt M, Altmeyer M, Anderson J, Eggert A, Dobbelstein M, Bayliss R, Chesler L, Büchel G, Eilers M. Roeschert I, et al. Among authors: buchel g. Nat Cancer. 2021 Mar;2(3):312-326. doi: 10.1038/s43018-020-00171-8. Epub 2021 Feb 11. Nat Cancer. 2021. PMID: 33768209 Free PMC article.
Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers.
Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GH, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, Penn LZ, Rape M, Roussel MF, Shokat KM, Tansey WP, Verba KA, Vos SM, Weiss WA, Wolf E, Mossé YP. Wolpaw AJ, et al. Among authors: buchel g. Cancer Res. 2021 Apr 1;81(7):1627-1632. doi: 10.1158/0008-5472.CAN-20-3108. Epub 2021 Jan 28. Cancer Res. 2021. PMID: 33509943 Free PMC article. Review.
Microbiomes in an acidic rock-water cave system.
Burow K, Grawunder A, Harpke M, Pietschmann S, Ehrhardt R, Wagner L, Voigt K, Merten D, Büchel G, Kothe E. Burow K, et al. Among authors: buchel g. FEMS Microbiol Lett. 2019 Jul 1;366(13):fnz167. doi: 10.1093/femsle/fnz167. FEMS Microbiol Lett. 2019. PMID: 31365079
48 results