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Assays for α-synuclein aggregation.
Giehm L, Lorenzen N, Otzen DE. Giehm L, et al. Among authors: otzen de. Methods. 2011 Mar;53(3):295-305. doi: 10.1016/j.ymeth.2010.12.008. Epub 2010 Dec 14. Methods. 2011. PMID: 21163351 Review.
Coexistence of ribbon and helical fibrils originating from hIAPP(20-29) revealed by quantitative nanomechanical atomic force microscopy.
Zhang S, Andreasen M, Nielsen JT, Liu L, Nielsen EH, Song J, Ji G, Sun F, Skrydstrup T, Besenbacher F, Nielsen NC, Otzen DE, Dong M. Zhang S, et al. Among authors: otzen de. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2798-803. doi: 10.1073/pnas.1209955110. Epub 2013 Feb 6. Proc Natl Acad Sci U S A. 2013. PMID: 23388629 Free PMC article.
Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization.
Underhaug J, Koldsø H, Runager K, Nielsen JT, Sørensen CS, Kristensen T, Otzen DE, Karring H, Malmendal A, Schiøtt B, Enghild JJ, Nielsen NC. Underhaug J, et al. Among authors: otzen de. Biochim Biophys Acta. 2013 Dec;1834(12):2812-22. doi: 10.1016/j.bbapap.2013.10.008. Epub 2013 Oct 12. Biochim Biophys Acta. 2013. PMID: 24129074 Free PMC article.
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.
Lorenzen N, Nielsen SB, Buell AK, Kaspersen JD, Arosio P, Vad BS, Paslawski W, Christiansen G, Valnickova-Hansen Z, Andreasen M, Enghild JJ, Pedersen JS, Dobson CM, Knowles TP, Otzen DE. Lorenzen N, et al. Among authors: otzen de. J Am Chem Soc. 2014 Mar 12;136(10):3859-68. doi: 10.1021/ja411577t. Epub 2014 Feb 28. J Am Chem Soc. 2014. PMID: 24527756
315 results