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Molecular profiling and specific targeting of gemcitabine-resistant subclones in heterogeneous pancreatic cancer cell populations.
Färber B, Lapshyna O, Künstner A, Kohl M, Sauer T, Bichmann K, Heckelmann B, Watzelt J, Honselmann K, Bolm L, Ten Winkel M, Busch H, Ungefroren H, Keck T, Gemoll T, Wellner UF, Braun R. Färber B, et al. Among authors: lapshyna o. Front Oncol. 2023 Aug 31;13:1230382. doi: 10.3389/fonc.2023.1230382. eCollection 2023. Front Oncol. 2023. PMID: 37719017 Free PMC article.
Establishment and Molecular Characterization of Two Patient-Derived Pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response.
Braun R, Lapshyna O, Watzelt J, Drenckhan M, Künstner A, Färber B, Hael AAM, Bolm L, Honselmann KC, Konukiewitz B, Castven D, Spielmann M, Gorantla SP, Busch H, Marquardt JU, Keck T, Wellner UF, Ungefroren H. Braun R, et al. Among authors: lapshyna o. Cells. 2023 Feb 11;12(4):587. doi: 10.3390/cells12040587. Cells. 2023. PMID: 36831254 Free PMC article.
Suppressive Role of ACVR1/ALK2 in Basal and TGFβ1-Induced Cell Migration in Pancreatic Ductal Adenocarcinoma Cells and Identification of a Self-Perpetuating Autoregulatory Loop Involving the Small GTPase RAC1b.
Ungefroren H, Braun R, Lapshyna O, Konukiewitz B, Wellner UF, Lehnert H, Marquardt JU. Ungefroren H, et al. Among authors: lapshyna o. Biomedicines. 2022 Oct 20;10(10):2640. doi: 10.3390/biomedicines10102640. Biomedicines. 2022. PMID: 36289908 Free PMC article.
A Comparative Endocrine Trans-Differentiation Approach to Pancreatic Ductal Adenocarcinoma Cells with Different EMT Phenotypes Identifies Quasi-Mesenchymal Tumor Cells as Those with Highest Plasticity.
Schmidtlein PM, Volz C, Braun R, Thürling I, Lapshyna O, Wellner UF, Konukiewitz B, Lehnert H, Marquardt JU, Ungefroren H. Schmidtlein PM, et al. Among authors: lapshyna o. Cancers (Basel). 2021 Sep 17;13(18):4663. doi: 10.3390/cancers13184663. Cancers (Basel). 2021. PMID: 34572891 Free PMC article.