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Modular synthesis of functional libraries by accelerated SuFEx click chemistry.
Homer JA, Koelln RA, Barrow AS, Gialelis TL, Boiarska Z, Steinohrt NS, Lee EF, Yang WH, Johnson RM, Chung T, Habowski AN, Vishwakarma DS, Bhunia D, Avanzi C, Moorhouse AD, Jackson M, Tuveson DA, Lyons SK, Lukey MJ, Fairlie WD, Haider SM, Steinmetz MO, Prota AE, Moses JE. Homer JA, et al. Among authors: fairlie wd. Chem Sci. 2024 Mar 4;15(11):3879-3892. doi: 10.1039/d3sc05729a. eCollection 2024 Mar 13. Chem Sci. 2024. PMID: 38487227 Free PMC article.
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer.
Jenkins LJ, Luk IY, Chionh F, Tan T, Needham K, Ayton J, Reehorst CM, Vukelic N, Sieber OM, Mouradov D, Gibbs P, Williams DS, Tebbutt NC, Desai J, Hollande F, Dhillon AS, Lee EF, Merino D, Fairlie WD, Mariadason JM. Jenkins LJ, et al. Among authors: fairlie wd. Cell Death Dis. 2024 Mar 1;15(3):183. doi: 10.1038/s41419-024-06478-z. Cell Death Dis. 2024. PMID: 38429301 Free PMC article.
Correction: ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors Across Tumor Types.
Chüeh AC, Tse JWT, Dickinson M, Ioannidis P, Jenkins L, Togel L, Tan B, Luk I, Davalos-Salas M, Nightingale R, Thompson MR, Williams BRG, Lessene G, Lee EF, Fairlie WD, Dhillon AS, Mariadason JM. Chüeh AC, et al. Among authors: fairlie wd. Clin Cancer Res. 2023 Sep 15;29(18):3826. doi: 10.1158/1078-0432.CCR-23-2100. Clin Cancer Res. 2023. PMID: 37712140 No abstract available.
Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death.
Jenkins LJ, Luk IY, Fairlie WD, Lee EF, Palmieri M, Schoffer KL, Tan T, Ng I, Vukelic N, Tran S, Tse JWT, Nightingale R, Alam Z, Chionh F, Iatropoulos G, Ernst M, Afshar-Sterle S, Desai J, Gibbs P, Sieber OM, Dhillon AS, Tebbutt NC, Mariadason JM. Jenkins LJ, et al. Among authors: fairlie wd. Mol Cancer Ther. 2023 Jan 3;22(1):52-62. doi: 10.1158/1535-7163.MCT-22-0101. Mol Cancer Ther. 2023. PMID: 36343387 Free PMC article.
BECLIN1: Protein Structure, Function and Regulation.
Tran S, Fairlie WD, Lee EF. Tran S, et al. Among authors: fairlie wd. Cells. 2021 Jun 17;10(6):1522. doi: 10.3390/cells10061522. Cells. 2021. PMID: 34204202 Free PMC article. Review.
109 results