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De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8.
Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zúniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D. Roy A, et al. Among authors: springer t. Nat Commun. 2023 Sep 13;14(1):5660. doi: 10.1038/s41467-023-41272-z. Nat Commun. 2023. PMID: 37704610 Free PMC article.
GARP regulates the bioavailability and activation of TGFβ.
Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA. Wang R, et al. Mol Biol Cell. 2012 Mar;23(6):1129-39. doi: 10.1091/mbc.E11-12-1018. Epub 2012 Jan 25. Mol Biol Cell. 2012. PMID: 22278742 Free PMC article.
Structure of bone morphogenetic protein 9 procomplex.
Mi LZ, Brown CT, Gao Y, Tian Y, Le VQ, Walz T, Springer TA. Mi LZ, et al. Among authors: springer ta. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3710-5. doi: 10.1073/pnas.1501303112. Epub 2015 Mar 6. Proc Natl Acad Sci U S A. 2015. PMID: 25751889 Free PMC article.
637 results