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The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling.
Sandner L, Alteneder M, Rica R, Woller B, Sala E, Frey T, Tosevska A, Zhu C, Madern M, Khan M, Hoffmann P, Schebesta A, Taniuchi I, Bonelli M, Schmetterer K, Iannacone M, Kuka M, Ellmeier W, Sakaguchi S, Herbst R, Boucheron N. Sandner L, et al. Among authors: schmetterer k. J Exp Med. 2023 Nov 6;220(11):e20221466. doi: 10.1084/jem.20221466. Epub 2023 Sep 13. J Exp Med. 2023. PMID: 37703004 Free PMC article.
The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells.
Mayer KA, Smole U, Zhu C, Derdak S, Minervina AA, Salnikova M, Witzeneder N, Christamentl A, Boucheron N, Waidhofer-Söllner P, Trauner M, Hoermann G, Schmetterer KG, Mamedov IZ, Bilban M, Ellmeier W, Pickl WF, Gualdoni GA, Zlabinger GJ. Mayer KA, et al. FASEB J. 2021 Apr;35(4):e21217. doi: 10.1096/fj.202001763RR. FASEB J. 2021. PMID: 33715236 Free PMC article.
Chloroquine inhibits human CD4+ T-cell activation by AP-1 signaling modulation.
Schmidt RL, Jutz S, Goldhahn K, Witzeneder N, Gerner MC, Trapin D, Greiner G, Hoermann G, Steiner G, Pickl WF, Burgmann H, Steinberger P, Ratzinger F, Schmetterer KG. Schmidt RL, et al. Among authors: schmetterer kg. Sci Rep. 2017 Feb 7;7:42191. doi: 10.1038/srep42191. Sci Rep. 2017. PMID: 28169350 Free PMC article.
Unreported Missense Mutation in the Dimerization Domain of ADA2 Leads to ADA2 Deficiency Associated with Severe Oral Ulcers and Neutropenia in a Female Somalian Patient-Addendum to the Genotype-Phenotype Puzzle.
Göschl L, Winkler S, Dmytrus J, Heredia RJ, Lagler H, Ramharter M, Scheinecker C, Bonelli M, Schmetterer K, Pickl WF, Grabmeier-Pfistershammer K, Hershfield MS, Boztug K, Förster-Waldl E, Gualdoni GA. Göschl L, et al. Among authors: schmetterer k. J Clin Immunol. 2020 Jan;40(1):223-226. doi: 10.1007/s10875-019-00700-w. Epub 2019 Nov 4. J Clin Immunol. 2020. PMID: 31686313 No abstract available.
Preclinical Establishment of a Divalent Vaccine against SARS-CoV-2.
Hevesi Z, Gerges DA, Kapps S, Freire R, Schmidt S, Pollak DD, Schmetterer K, Frey T, Lang R, Winnicki W, Schmidt A, Harkany T, Wagner L. Hevesi Z, et al. Among authors: schmetterer k. Vaccines (Basel). 2022 Mar 26;10(4):516. doi: 10.3390/vaccines10040516. Vaccines (Basel). 2022. PMID: 35455265 Free PMC article.
Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation.
Reithofer M, Karacs J, Strobl J, Kitzmüller C, Polak D, Seif K, Kamalov M, Becker CFW, Greiner G, Schmetterer K, Stary G, Bohle B, Jahn-Schmid B. Reithofer M, et al. Among authors: schmetterer k. FASEB J. 2020 Oct;34(10):14024-14041. doi: 10.1096/fj.202001413R. Epub 2020 Aug 29. FASEB J. 2020. PMID: 32860638 Free PMC article.
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