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Sterile triggers drive joint inflammation in TNF- and IL-1β-dependent mouse arthritis models.
Thiran A, Petta I, Blancke G, Thorp M, Planckaert G, Jans M, Andries V, Barbry K, Gilis E, Coudenys J, Hochepied T, Vanhove C, Gracey E, Dumas E, Manuelo T, Josipovic I, van Loo G, Elewaut D, Vereecke L. Thiran A, et al. Among authors: vanhove c. EMBO Mol Med. 2023 Oct 11;15(10):e17691. doi: 10.15252/emmm.202317691. Epub 2023 Sep 11. EMBO Mol Med. 2023. PMID: 37694693 Free PMC article.
Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Van Welden S, De Vos M, Wielockx B, Tavernier SJ, Dullaers M, Neyt S, Descamps B, Devisscher L, Devriese S, Van den Bossche L, Holvoet T, Baeyens A, Correale C, D'Alessio S, Vanhove C, De Vos F, Verhasselt B, Breier G, Lambrecht BN, Janssens S, Carmeliet P, Danese S, Elewaut D, Laukens D, Hindryckx P. Van Welden S, et al. Among authors: vanhove c. J Pathol. 2017 Mar;241(4):547-558. doi: 10.1002/path.4861. Epub 2017 Jan 27. J Pathol. 2017. PMID: 27981571
STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity.
Maes B, Fayazpour F, Catrysse L, Lornet G, Van De Velde E, De Wolf C, De Prijck S, Van Moorleghem J, Vanheerswynghels M, Deswarte K, Descamps B, Vanhove C, Van der Schueren B, Vangoitsenhoven R, Hammad H, Janssens S, Lambrecht BN. Maes B, et al. Among authors: vanhove c. J Exp Med. 2023 Sep 4;220(9):e20210788. doi: 10.1084/jem.20210788. Epub 2023 Jun 22. J Exp Med. 2023. PMID: 37347461 Free PMC article.
TNFR1 inhibition with a Nanobody protects against EAE development in mice.
Steeland S, Van Ryckeghem S, Van Imschoot G, De Rycke R, Toussaint W, Vanhoutte L, Vanhove C, De Vos F, Vandenbroucke RE, Libert C. Steeland S, et al. Among authors: vanhove c. Sci Rep. 2017 Oct 20;7(1):13646. doi: 10.1038/s41598-017-13984-y. Sci Rep. 2017. PMID: 29057962 Free PMC article.
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping.
Naert T, Tulkens D, Van Nieuwenhuysen T, Przybyl J, Demuynck S, van de Rijn M, Al-Jazrawe M, Alman BA, Coucke PJ, De Leeneer K, Vanhove C, Savvides SN, Creytens D, Vleminckx K. Naert T, et al. Among authors: vanhove c. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2115116118. doi: 10.1073/pnas.2115116118. Proc Natl Acad Sci U S A. 2021. PMID: 34789568 Free PMC article.
191 results