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Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility.
Basic Res Cardiol. 2023 Sep 9;118(1):37. doi: 10.1007/s00395-023-01008-y.
Basic Res Cardiol. 2023.
PMID: 37688627
Free PMC article.
Hemodynamic Effects of Ketone Bodies in Patients With Pulmonary Hypertension.
Nielsen R, Christensen KH, Gopalasingam N, Berg-Hansen K, Seefeldt J, Homilius C, Boedtkjer E, Andersen MJ, Wiggers H, Møller N, Bøtker HE, Mellemkjær S.
Nielsen R, et al. Among authors: homilius c.
J Am Heart Assoc. 2023 May 16;12(10):e028232. doi: 10.1161/JAHA.122.028232. Epub 2023 May 15.
J Am Heart Assoc. 2023.
PMID: 37183871
Free PMC article.
Clinical Trial.
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PTPRG is an ischemia risk locus essential for HCO3--dependent regulation of endothelial function and tissue perfusion.
Hansen KB, Staehr C, Rohde PD, Homilius C, Kim S, Nyegaard M, Matchkov VV, Boedtkjer E.
Hansen KB, et al. Among authors: homilius c.
Elife. 2020 Sep 21;9:e57553. doi: 10.7554/eLife.57553.
Elife. 2020.
PMID: 32955439
Free PMC article.
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Upregulated Na+/H+-Exchange Protects Human Colon Cancer Tissue against Intracellular Acidification.
Voss NCS, Kold-Petersen H, Henningsen MB, Homilius C, Boedtkjer E.
Voss NCS, et al. Among authors: homilius c.
Biomed Res Int. 2019 Jan 29;2019:3702783. doi: 10.1155/2019/3702783. eCollection 2019.
Biomed Res Int. 2019.
PMID: 30834261
Free PMC article.
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Short-Chain Fatty Acid Butyrate Is an Inotropic Agent With Vasorelaxant and Cardioprotective Properties.
Seefeldt JM, Homilius C, Hansen J, Lassen TR, Jespersen NR, Jensen RV, Boedtkjer E, Bøtker HE, Nielsen R.
Seefeldt JM, et al. Among authors: homilius c.
J Am Heart Assoc. 2024 May 7;13(9):e033744. doi: 10.1161/JAHA.123.033744. Epub 2024 Apr 30.
J Am Heart Assoc. 2024.
PMID: 38686853
Free article.
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Enantiomer-Specific Cardiovascular Effects of the Ketone Body 3-Hydroxybutyrate.
Gopalasingam N, Moeslund N, Christensen KH, Berg-Hansen K, Seefeldt J, Homilius C, Nielsen EN, Dollerup MR, Alstrup Olsen AK, Johannsen M, Boedtkjer E, Møller N, Eiskjær H, Gormsen LC, Nielsen R, Wiggers H.
Gopalasingam N, et al. Among authors: homilius c.
J Am Heart Assoc. 2024 Apr 16;13(8):e033628. doi: 10.1161/JAHA.123.033628. Epub 2024 Apr 2.
J Am Heart Assoc. 2024.
PMID: 38563382
Free article.
Clinical Trial.
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