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Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling.
Angus L, Smid M, Wilting SM, Bos MK, Steeghs N, Konings IRHM, Tjan-Heijnen VCG, van Riel JMGH, van de Wouw AJ, Cpct Consortium, Cuppen E, Lolkema MP, Jager A, Sleijfer S, Martens JWM. Angus L, et al. Cancers (Basel). 2023 Sep 4;15(17):4416. doi: 10.3390/cancers15174416. Cancers (Basel). 2023. PMID: 37686693 Free PMC article.
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.
Angus L, Smid M, Wilting SM, van Riet J, Van Hoeck A, Nguyen L, Nik-Zainal S, Steenbruggen TG, Tjan-Heijnen VCG, Labots M, van Riel JMGH, Bloemendal HJ, Steeghs N, Lolkema MP, Voest EE, van de Werken HJG, Jager A, Cuppen E, Sleijfer S, Martens JWM. Angus L, et al. Nat Genet. 2019 Oct;51(10):1450-1458. doi: 10.1038/s41588-019-0507-7. Epub 2019 Sep 30. Nat Genet. 2019. PMID: 31570896 Free PMC article.
Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features.
Mendelaar PAJ, Smid M, van Riet J, Angus L, Labots M, Steeghs N, Hendriks MP, Cirkel GA, van Rooijen JM, Ten Tije AJ, Lolkema MP, Cuppen E, Sleijfer S, Martens JWM, Wilting SM. Mendelaar PAJ, et al. Among authors: angus l. Nat Commun. 2021 Jan 25;12(1):574. doi: 10.1038/s41467-020-20887-6. Nat Commun. 2021. PMID: 33495476 Free PMC article.
Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features.
Mendelaar PAJ, Smid M, van Riet J, Angus L, Labots M, Steeghs N, Hendriks MP, Cirkel GA, van Rooijen JM, Ten Tije AJ, Lolkema MP, Cuppen E, Sleijfer S, Martens JWM, Wilting SM. Mendelaar PAJ, et al. Among authors: angus l. Nat Commun. 2021 May 26;12(1):3269. doi: 10.1038/s41467-021-23629-4. Nat Commun. 2021. PMID: 34039979 Free PMC article. No abstract available.
High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments.
Deger T, Boers RG, de Weerd V, Angus L, van der Put MMJ, Boers JB, Azmani Z, van IJcken WFJ, Grünhagen DJ, van Dessel LF, Lolkema MPJK, Verhoef C, Sleijfer S, Martens JWM, Gribnau J, Wilting SM. Deger T, et al. Among authors: angus l. Clin Epigenetics. 2021 Oct 20;13(1):196. doi: 10.1186/s13148-021-01177-4. Clin Epigenetics. 2021. PMID: 34670587 Free PMC article.
Prospective Evaluation of a Circulating Tumor Cell Sensitivity Profile to Predict Response to Cisplatin Chemotherapy in Metastatic Breast Cancer Patients.
de Kruijff IE, Sieuwerts AM, Beije N, Prager-van der Smissen WJC, Angus L, Beaufort CM, Van MN, Oomen-de Hoop E, Jager A, Hamberg P, de Jongh FE, Kraan J, Martens JWM, Sleijfer S. de Kruijff IE, et al. Among authors: angus l. Front Oncol. 2021 Jun 25;11:697572. doi: 10.3389/fonc.2021.697572. eCollection 2021. Front Oncol. 2021. PMID: 34249756 Free PMC article.
An Optimized Workflow to Evaluate Estrogen Receptor Gene Mutations in Small Amounts of Cell-Free DNA.
Vitale SR, Sieuwerts AM, Beije N, Kraan J, Angus L, Mostert B, Reijm EA, Van NM, van Marion R, Dirix LY, Hamberg P, de Jongh FE, Jager A, Foekens JA, Vigneri P, Sleijfer S, Jansen MPHM, Martens JWM. Vitale SR, et al. Among authors: angus l. J Mol Diagn. 2019 Jan;21(1):123-137. doi: 10.1016/j.jmoldx.2018.08.010. Epub 2018 Oct 6. J Mol Diagn. 2019. PMID: 30296589 Free article.
171 results