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IL-6 trans-signaling in a humanized mouse model of scleroderma.
Odell ID, Agrawal K, Sefik E, Odell AV, Caves E, Kirkiles-Smith NC, Horsley V, Hinchcliff M, Pober JS, Kluger Y, Flavell RA. Odell ID, et al. Among authors: flavell ra. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2306965120. doi: 10.1073/pnas.2306965120. Epub 2023 Sep 5. Proc Natl Acad Sci U S A. 2023. PMID: 37669366 Free PMC article.
IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory.
Micevic G, Daniels A, Flem-Karlsen K, Park K, Talty R, McGeary M, Mirza H, Blackburn HN, Sefik E, Cheung JF, Hornick NI, Aizenbud L, Joshi NS, Kluger H, Iwasaki A, Bosenberg MW, Flavell RA. Micevic G, et al. Among authors: flavell ra. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2304319120. doi: 10.1073/pnas.2304319120. Epub 2023 Jul 17. Proc Natl Acad Sci U S A. 2023. PMID: 37459511 Free PMC article.
Activation of CD4 T cells by Raf-independent effectors of Ras.
Czyzyk J, Brogdon JL, Badou A, Henegariu O, Preston Hurlburt P, Flavell R, Bottomly K. Czyzyk J, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6003-8. doi: 10.1073/pnas.1031494100. Epub 2003 Apr 29. Proc Natl Acad Sci U S A. 2003. PMID: 12721365 Free PMC article.
Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes.
Martinez-Sanz P, Laurent ARG, Slot E, Hoogenboezem M, Bąbała N, van Bruggen R, Rongvaux A, Flavell RA, Tytgat GAM, Franke K, Matlung HL, Kuijpers TW, Amsen D, Karrich JJ. Martinez-Sanz P, et al. Among authors: flavell ra. Front Immunol. 2023 Mar 8;14:1105103. doi: 10.3389/fimmu.2023.1105103. eCollection 2023. Front Immunol. 2023. PMID: 36969261 Free PMC article.
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22.
Giannou AD, Kempski J, Shiri AM, Lücke J, Zhang T, Zhao L, Zazara DE, Cortesi F, Riecken K, Amezcua Vesely MC, Low JS, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens KF, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber FJ, Reeh M, Grass JK, Wahib R, Seese H, Stüben BO, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis IC, Arck PC, Perez D, Gao B, Zarogiannis SG, Strowig T, Pasqualini R, Arap W, Gosálvez JS, Kobold S, Prinz I, Guse AH, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki JR, Pantel K, Schumacher U, Lohse AW, Flavell RA, Gagliani N, Huber S. Giannou AD, et al. Among authors: flavell ra. Immunity. 2023 Jan 10;56(1):125-142.e12. doi: 10.1016/j.immuni.2022.12.014. Immunity. 2023. PMID: 36630911 Free PMC article.
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.
Hackstein CP, Spitzer J, Symeonidis K, Horvatic H, Bedke T, Steglich B, Klein S, Assmus LM, Odainic A, Szlapa J, Kessler N, Beyer M, Schmithausen R, Latz E, Flavell RA, Garbi N, Kurts C, Kümmerer BM, Trebicka J, Roers A, Huber S, Schmidt SV, Knolle PA, Abdullah Z. Hackstein CP, et al. Among authors: flavell ra. J Hepatol. 2023 Jul;79(1):150-166. doi: 10.1016/j.jhep.2023.02.026. Epub 2023 Mar 2. J Hepatol. 2023. PMID: 36870611 Free article.
1,211 results