Yamazaki S - Search Results

1

Physiologically-based pharmacokinetic modeling for investigating the effect of simeprevir on concomitant drugs and an endogenous biomarker of OATP1B.

Nakayama S, Toshimoto K, Yamazaki S, Snoeys J, Sugiyama Y. Nakayama S, et al. Among authors: yamazaki s. CPT Pharmacometrics Syst Pharmacol. 2023 Oct;12(10):1461-1472. doi: 10.1002/psp4.13023. Epub 2023 Sep 4. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37667529 Free PMC article.

2

Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction.

Yamazaki S, Costales C, Lazzaro S, Eatemadpour S, Kimoto E, Varma MV. Yamazaki S, et al. CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):634-642. doi: 10.1002/psp4.12458. Epub 2019 Sep 5. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31420942 Free PMC article.

3

Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition.

Yamazaki S, Evers R, De Zwart L. Yamazaki S, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Jan;11(1):55-67. doi: 10.1002/psp4.12733. Epub 2021 Nov 6. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 34668334 Free PMC article.

4

Quantitative prediction of breast cancer resistant protein mediated drug-drug interactions using physiologically-based pharmacokinetic modeling.

Costales C, Lin J, Kimoto E, Yamazaki S, Gosset JR, Rodrigues AD, Lazzaro S, West MA, West M, Varma MVS. Costales C, et al. Among authors: yamazaki s. CPT Pharmacometrics Syst Pharmacol. 2021 Sep;10(9):1018-1031. doi: 10.1002/psp4.12672. Epub 2021 Jul 20. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34164937 Free PMC article.

5

Unraveling pleiotropic effects of rifampicin by using physiologically based pharmacokinetic modeling: Assessing the induction magnitude of P-glycoprotein-cytochrome P450 3A4 dual substrates.

Pan X, Yamazaki S, Neuhoff S, Zhang M, Pilla Reddy V. Pan X, et al. Among authors: yamazaki s. CPT Pharmacometrics Syst Pharmacol. 2021 Dec;10(12):1485-1496. doi: 10.1002/psp4.12717. Epub 2021 Nov 2. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34729944 Free PMC article.

6

Physiologically-based pharmacokinetic modeling for primary metabolites of CYP3A and P-glycoprotein inhibitors in drug-drug interactions: Should we assume the free drug hypothesis?

Yamazaki S, Evers R, De Zwart L. Yamazaki S, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Jan;12(1):8-12. doi: 10.1002/psp4.12879. Epub 2022 Nov 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36369633 Free PMC article. No abstract available.

7

Effect of Hepatic Impairment on OATP1B Activity: Quantitative Pharmacokinetic Analysis of Endogenous Biomarker and Substrate Drugs.

Lin J, Kimoto E, Yamazaki S, Vourvahis M, Bergman A, Rodrigues AD, Costales C, Li R, Varma MVS. Lin J, et al. Among authors: yamazaki s. Clin Pharmacol Ther. 2023 May;113(5):1058-1069. doi: 10.1002/cpt.2829. Epub 2023 Jan 15. Clin Pharmacol Ther. 2023. PMID: 36524426

8

Relationships of Changes in Pharmacokinetic Parameters of Substrate Drugs in Drug-Drug Interactions on Metabolizing Enzymes and Transporters.

Yamazaki S. Yamazaki S. J Clin Pharmacol. 2018 Aug;58(8):1053-1060. doi: 10.1002/jcph.1104. Epub 2018 May 3. J Clin Pharmacol. 2018. PMID: 29723430

9

Translation of anticancer efficacy from nonclinical models to the clinic.

Stroh M, Duda DG, Takimoto CH, Yamazaki S, Vicini P. Stroh M, et al. Among authors: yamazaki s. CPT Pharmacometrics Syst Pharmacol. 2014 Aug 6;3(8):e128. doi: 10.1038/psp.2014.28. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25098530 Free PMC article.

10

Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug-Drug and Drug-Disease Interactions.

Ono C, Hsyu PH, Abbas R, Loi CM, Yamazaki S. Ono C, et al. Among authors: yamazaki s. Drug Metab Dispos. 2017 Apr;45(4):390-398. doi: 10.1124/dmd.116.074450. Epub 2017 Feb 6. Drug Metab Dispos. 2017. PMID: 28167538

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