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Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoin.
Ramirez-Hincapie S, Birk B, Ternes P, Giri V, Zickgraf FM, Haake V, Herold M, Kamp H, Driemert P, Landsiedel R, Richling E, Funk-Weyer D, van Ravenzwaay B. Ramirez-Hincapie S, et al. Among authors: zickgraf fm. Arch Toxicol. 2023 Nov;97(11):2903-2917. doi: 10.1007/s00204-023-03572-7. Epub 2023 Sep 4. Arch Toxicol. 2023. PMID: 37665362 Free PMC article.
A high-throughput metabolomics in vitro platform for the characterization of hepatotoxicity.
Ramirez-Hincapie S, Birk B, Ternes P, Giri V, Haake V, Herold M, Zickgraf FM, Verlohner A, Huener HA, Kamp H, Driemert P, Landsiedel R, Richling E, Funk-Weyer D, van Ravenzwaay B. Ramirez-Hincapie S, et al. Among authors: zickgraf fm. Cell Biol Toxicol. 2023 Dec;39(6):2899-2917. doi: 10.1007/s10565-023-09809-6. Epub 2023 May 4. Cell Biol Toxicol. 2023. PMID: 37138123 Free PMC article.
Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice.
Viant MR, Amstalden E, Athersuch T, Bouhifd M, Camuzeaux S, Crizer DM, Driemert P, Ebbels T, Ekman D, Flick B, Giri V, Gómez-Romero M, Haake V, Herold M, Kende A, Lai F, Leonards PEG, Lim PP, Lloyd GR, Mosley J, Namini C, Rice JR, Romano S, Sands C, Smith MJ, Sobanski T, Southam AD, Swindale L, van Ravenzwaay B, Walk T, Weber RJM, Zickgraf FM, Kamp H. Viant MR, et al. Among authors: zickgraf fm. Arch Toxicol. 2024 Apr;98(4):1111-1123. doi: 10.1007/s00204-024-03680-y. Epub 2024 Feb 18. Arch Toxicol. 2024. PMID: 38368582 Free PMC article.
A metabolomics approach to reveal the mechanism of developmental toxicity in zebrafish embryos exposed to 6-propyl-2-thiouracil.
Wilhelmi P, Giri V, Zickgraf FM, Haake V, Henkes S, Driemert P, Michaelis P, Busch W, Scholz S, Flick B, Barenys M, Birk B, Kamp H, Landsiedel R, Funk-Weyer D. Wilhelmi P, et al. Among authors: zickgraf fm. Chem Biol Interact. 2023 Sep 1;382:110565. doi: 10.1016/j.cbi.2023.110565. Epub 2023 May 24. Chem Biol Interact. 2023. PMID: 37236578 Free article.
Connecting Gut Microbial Diversity with Plasma Metabolome and Fecal Bile Acid Changes Induced by the Antibiotics Tobramycin and Colistin Sulfate.
Murali A, Giri V, Zickgraf FM, Ternes P, Cameron HJ, Sperber S, Haake V, Driemert P, Kamp H, Funk-Weyer D, Sturla SJ, Rietjens IMCM, van Ravenzwaay B. Murali A, et al. Among authors: zickgraf fm. Chem Res Toxicol. 2023 Apr 17;36(4):598-616. doi: 10.1021/acs.chemrestox.2c00316. Epub 2023 Mar 27. Chem Res Toxicol. 2023. PMID: 36972423
Therapy resistance on the RADar in ovarian cancer.
Schwickert J, Zickgraf FM, Sprick MR. Schwickert J, et al. Among authors: zickgraf fm. EMBO Mol Med. 2021 May 7;13(5):e14010. doi: 10.15252/emmm.202114010. Epub 2021 Mar 29. EMBO Mol Med. 2021. PMID: 33779077 Free PMC article.
12 results