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Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoin.
Ramirez-Hincapie S, Birk B, Ternes P, Giri V, Zickgraf FM, Haake V, Herold M, Kamp H, Driemert P, Landsiedel R, Richling E, Funk-Weyer D, van Ravenzwaay B. Ramirez-Hincapie S, et al. Among authors: kamp h. Arch Toxicol. 2023 Nov;97(11):2903-2917. doi: 10.1007/s00204-023-03572-7. Epub 2023 Sep 4. Arch Toxicol. 2023. PMID: 37665362 Free PMC article.
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, Harbell J, Hartung T, Kamp H, Varlet BL, Meloni M, McNamee P, Osborne R, Pape W, Pfannenbecker U, Prinsen M, Seaman C, Spielmann H, Stokes W, Trouba K, Berghe CV, Goethem FV, Vassallo M, Vinardell P, Zuang V. Scott L, et al. Among authors: kamp h. Toxicol In Vitro. 2010 Feb;24(1):1-9. doi: 10.1016/j.tiv.2009.05.019. Epub 2009 May 31. Toxicol In Vitro. 2010. PMID: 19490935 Review.
Reconstructed human epidermis for skin absorption testing: results of the German prevalidation study.
Schäfer-Korting M, Bock U, Gamer A, Haberland A, Haltner-Ukomadu E, Kaca M, Kamp H, Kietzmann M, Korting HC, Krächter HU, Lehr CM, Liebsch M, Mehling A, Netzlaff F, Niedorf F, Rübbelke MK, Schäfer U, Schmidt E, Schreiber S, Schröder KR, Spielmann H, Vuia A. Schäfer-Korting M, et al. Among authors: kamp h. Altern Lab Anim. 2006 Jun;34(3):283-94. doi: 10.1177/026119290603400312. Altern Lab Anim. 2006. PMID: 16831060
The individual and combined metabolite profiles (metabolomics) of dibutylphthalate and di(2-ethylhexyl)phthalate following a 28-day dietary exposure in rats.
van Ravenzwaay B, Coelho-Palermo Cunha G, Strauss V, Wiemer J, Leibold E, Kamp H, Walk T, Mellert W, Looser R, Prokoudine A, Fabian E, Krennrich G, Herold M. van Ravenzwaay B, et al. Among authors: kamp h. Toxicol Lett. 2010 Oct 5;198(2):159-70. doi: 10.1016/j.toxlet.2010.06.009. Epub 2010 Jun 23. Toxicol Lett. 2010. PMID: 20600714
Nutritional impact on the plasma metabolome of rats.
Mellert W, Kapp M, Strauss V, Wiemer J, Kamp H, Walk T, Looser R, Prokoudine A, Fabian E, Krennrich G, Herold M, van Ravenzwaay B. Mellert W, et al. Among authors: kamp h. Toxicol Lett. 2011 Nov 30;207(2):173-81. doi: 10.1016/j.toxlet.2011.08.013. Epub 2011 Sep 3. Toxicol Lett. 2011. PMID: 21907771
200 results