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Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance.
J Clin Invest. 2023 Nov 1;133(21):e167951. doi: 10.1172/JCI167951.
J Clin Invest. 2023.
PMID: 37651197
Free PMC article.
The innate immune receptor TREM-1 promotes liver injury and fibrosis.
Nguyen-Lefebvre AT, Ajith A, Portik-Dobos V, Horuzsko DD, Arbab AS, Dzutsev A, Sadek R, Trinchieri G, Horuzsko A.
Nguyen-Lefebvre AT, et al. Among authors: horuzsko dd.
J Clin Invest. 2018 Nov 1;128(11):4870-4883. doi: 10.1172/JCI98156. Epub 2018 Oct 2.
J Clin Invest. 2018.
PMID: 30137027
Free PMC article.
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IL-10-producing memory B regulatory cells as a novel target for HLA-G to prolong human kidney allograft survival.
Ajith A, Mamouni K, Musa A, Horuzsko DD, Gani I, Mulloy LL, Horuzsko A.
Ajith A, et al. Among authors: horuzsko dd.
Hum Immunol. 2023 Aug;84(8):366-373. doi: 10.1016/j.humimm.2023.03.003. Epub 2023 Mar 16.
Hum Immunol. 2023.
PMID: 36934068
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HLA-G dimer targets Granzyme B pathway to prolong human renal allograft survival.
Ajith A, Portik-Dobos V, Nguyen-Lefebvre AT, Callaway C, Horuzsko DD, Kapoor R, Zayas C, Maenaka K, Mulloy LL, Horuzsko A.
Ajith A, et al. Among authors: horuzsko dd.
FASEB J. 2019 Apr;33(4):5220-5236. doi: 10.1096/fj.201802017R. Epub 2019 Jan 8.
FASEB J. 2019.
PMID: 30620626
Free PMC article.
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Humanized Mouse Model as a Novel Approach in the Assessment of Human Allogeneic Responses in Organ Transplantation.
Ajith A, Mulloy LL, Musa MA, Bravo-Egana V, Horuzsko DD, Gani I, Horuzsko A.
Ajith A, et al. Among authors: horuzsko dd.
Front Immunol. 2021 Jun 11;12:687715. doi: 10.3389/fimmu.2021.687715. eCollection 2021.
Front Immunol. 2021.
PMID: 34177940
Free PMC article.
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Mouse models for studies of HLA-G functions in basic science and pre-clinical research.
Nguyen-Lefebvre AT, Ajith A, Portik-Dobos V, Horuzsko DD, Mulloy LL, Horuzsko A.
Nguyen-Lefebvre AT, et al. Among authors: horuzsko dd.
Hum Immunol. 2016 Sep;77(9):711-9. doi: 10.1016/j.humimm.2016.02.012. Epub 2016 Apr 13.
Hum Immunol. 2016.
PMID: 27085792
Review.
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HLA-G and humanized mouse models as a novel therapeutic approach in transplantation.
Ajith A, Portik-Dobos V, Horuzsko DD, Kapoor R, Mulloy LL, Horuzsko A.
Ajith A, et al. Among authors: horuzsko dd.
Hum Immunol. 2020 Apr;81(4):178-185. doi: 10.1016/j.humimm.2020.02.006. Epub 2020 Feb 21.
Hum Immunol. 2020.
PMID: 32093884
Free PMC article.
Review.
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HLA-G dimers in the prolongation of kidney allograft survival.
Ezeakile M, Portik-Dobos V, Wu J, Horuzsko DD, Kapoor R, Jagadeesan M, Mulloy LL, Horuzsko A.
Ezeakile M, et al. Among authors: horuzsko dd.
J Immunol Res. 2014;2014:153981. doi: 10.1155/2014/153981. Epub 2014 Mar 30.
J Immunol Res. 2014.
PMID: 24741575
Free PMC article.
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