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MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer.
Bhin J, Yemelyanenko J, Chao X, Klarenbeek S, Opdam M, Malka Y, Hoekman L, Kruger D, Bleijerveld O, Brambillasca CS, Sprengers J, Siteur B, Annunziato S, van Haren MJ, Martin NI, van de Ven M, Peters D, Agami R, Linn SC, Boven E, Altelaar M, Jonkers J, Zingg D, Wessels LFA. Bhin J, et al. Among authors: malka y. J Exp Med. 2023 Nov 6;220(11):e20211743. doi: 10.1084/jem.20211743. Epub 2023 Aug 29. J Exp Med. 2023. PMID: 37642941 Free PMC article.
Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness.
Lin CP, Levy PL, Alflen A, Apriamashvili G, Ligtenberg MA, Vredevoogd DW, Bleijerveld OB, Alkan F, Malka Y, Hoekman L, Markovits E, George A, Traets JJH, Krijgsman O, van Vliet A, Poźniak J, Pulido-Vicuña CA, de Bruijn B, van Hal-van Veen SE, Boshuizen J, van der Helm PW, Díaz-Gómez J, Warda H, Behrens LM, Mardesic P, Dehni B, Visser NL, Marine JC, Markel G, Faller WJ, Altelaar M, Agami R, Besser MJ, Peeper DS. Lin CP, et al. Among authors: malka y. Cancer Cell. 2024 Apr 8;42(4):623-645.e10. doi: 10.1016/j.ccell.2024.02.016. Epub 2024 Mar 14. Cancer Cell. 2024. PMID: 38490212 Free PMC article.
DNA damage induces p53-independent apoptosis through ribosome stalling.
Boon NJ, Oliveira RA, Körner PR, Kochavi A, Mertens S, Malka Y, Voogd R, van der Horst SEM, Huismans MA, Smabers LP, Draper JM, Wessels LFA, Haahr P, Roodhart JML, Schumacher TNM, Snippert HJ, Agami R, Brummelkamp TR. Boon NJ, et al. Among authors: malka y. Science. 2024 May 17;384(6697):785-792. doi: 10.1126/science.adh7950. Epub 2024 May 16. Science. 2024. PMID: 38753784
[An adrenal incidentaloma which should not be underestimated].
Bitton L, Malka Y, Varinot J, Buob D. Bitton L, et al. Among authors: malka y. Ann Pathol. 2023 Mar;43(2):153-156. doi: 10.1016/j.annpat.2023.02.004. Epub 2023 Mar 3. Ann Pathol. 2023. PMID: 36872168 French. No abstract available.
17 results