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Exploring effects of remote ischemic preconditioning in a pig model of hypothermic circulatory arrest.
Herajärvi J, Anttila T, Dimova EY, Laukka T, Myllymäki M, Haapanen H, Olenchock BA, Tuominen H, Puistola U, Karihtala P, Kiviluoma K, Koivunen P, Anttila V, Juvonen T. Herajärvi J, et al. Among authors: koivunen p. Scand Cardiovasc J. 2017 Aug;51(4):233-241. doi: 10.1080/14017431.2017.1319574. Epub 2017 Apr 24. Scand Cardiovasc J. 2017. PMID: 28434264
Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection.
Kerkelä R, Karsikas S, Szabo Z, Serpi R, Magga J, Gao E, Alitalo K, Anisimov A, Sormunen R, Pietilä I, Vainio L, Koch WJ, Kivirikko KI, Myllyharju J, Koivunen P. Kerkelä R, et al. Among authors: koivunen p. Mol Cell Biol. 2013 Aug;33(16):3321-9. doi: 10.1128/MCB.00432-13. Epub 2013 Jun 17. Mol Cell Biol. 2013. PMID: 23775121 Free PMC article.
Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia.
Auvinen J, Tapio J, Karhunen V, Kettunen J, Serpi R, Dimova EY, Gill D, Soininen P, Tammelin T, Mykkänen J, Puukka K, Kähönen M, Raitoharju E, Lehtimäki T, Ala-Korpela M, Raitakari OT, Keinänen-Kiukaanniemi S, Järvelin MR, Koivunen P. Auvinen J, et al. Among authors: koivunen p. Sci Adv. 2021 Jul 14;7(29):eabi4822. doi: 10.1126/sciadv.abi4822. Print 2021 Jul. Sci Adv. 2021. PMID: 34261659 Free PMC article.
Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation.
Byts N, Sharma S, Malm T, Kaakinen M, Korhonen P, Jaakkonen L, Keuters M, Huuskonen M, Pietilä I, Koistinaho J, Koivunen P, Myllyharju J. Byts N, et al. Among authors: koivunen p. J Biol Chem. 2022 Mar;298(3):101721. doi: 10.1016/j.jbc.2022.101721. Epub 2022 Feb 11. J Biol Chem. 2022. PMID: 35151685 Free PMC article.
Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy.
Röning T, Magga J, Laitakari A, Halmetoja R, Tapio J, Dimova EY, Szabo Z, Rahtu-Korpela L, Kemppi A, Walkinshaw G, Myllyharju J, Kerkelä R, Koivunen P, Serpi R. Röning T, et al. Among authors: koivunen p. J Mol Cell Cardiol. 2022 Mar;164:148-155. doi: 10.1016/j.yjmcc.2021.12.003. Epub 2021 Dec 14. J Mol Cell Cardiol. 2022. PMID: 34919895 Free article.
211 results